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Julia Joung

Explore the profile of Julia Joung including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 11418
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Recent Articles
11.
Schermer B, Fabretti F, Damagnez M, Di Cristanziano V, Heger E, Arjune S, et al.
PLoS One . 2020 Nov; 15(11):e0238612. PMID: 33137122
Background: Rapid and extensive testing of large parts of the population and specific subgroups is crucial for proper management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and decision-making...
12.
Joung J, Ladha A, Saito M, Kim N, Woolley A, Segel M, et al.
N Engl J Med . 2020 Sep; 383(15):1492-1494. PMID: 32937062
No abstract available.
13.
Patchsung M, Jantarug K, Pattama A, Aphicho K, Suraritdechachai S, Meesawat P, et al.
Nat Biomed Eng . 2020 Aug; 4(12):1140-1149. PMID: 32848209
Nucleic acid detection by isothermal amplification and the collateral cleavage of reporter molecules by CRISPR-associated enzymes is a promising alternative to quantitative PCR. Here, we report the clinical validation of...
14.
Joung J, Ladha A, Saito M, Segel M, Bruneau R, Huang M, et al.
medRxiv . 2020 Jun; PMID: 32511521
The recent outbreak of the novel coronavirus SARS-CoV-2, which causes COVID-19, can be diagnosed using RT-qPCR, but inadequate access to reagents and equipment has slowed disease detection and impeded efforts...
15.
So R, Chung S, Lau H, Watts J, Gaudette E, Al-Azzawi Z, et al.
Mol Neurodegener . 2019 Nov; 14(1):41. PMID: 31727120
The adoption of CRISPR-Cas9 technology for functional genetic screens has been a transformative advance. Due to its modular nature, this technology can be customized to address a myriad of questions....
16.
Abudayyeh O, Gootenberg J, Franklin B, Koob J, Kellner M, Ladha A, et al.
Science . 2019 Jul; 365(6451):382-386. PMID: 31296651
Programmable RNA editing enables reversible recoding of RNA information for research and disease treatment. Previously, we developed a programmable adenosine-to-inosine (A-to-I) RNA editing approach by fusing catalytically inactivate RNA-targeting CRISPR-Cas13...
17.
Joung J, Konermann S, Gootenberg J, Abudayyeh O, Platt R, Brigham M, et al.
Nat Protoc . 2018 Oct; 14(7):2259. PMID: 30349047
In the published version of this paper, Step 64 of the Procedure reads, "Refer to Steps 37-39 for NGS analysis of the sgRNA distribution." This step should refer the reader...
18.
Gootenberg J, Abudayyeh O, Kellner M, Joung J, Collins J, Zhang F
Science . 2018 Feb; 360(6387):439-444. PMID: 29449508
Rapid detection of nucleic acids is integral for clinical diagnostics and biotechnological applications. We recently developed a platform termed SHERLOCK (specific high-sensitivity enzymatic reporter unlocking) that combines isothermal preamplification with...
19.
Cox D, Gootenberg J, Abudayyeh O, Franklin B, Kellner M, Joung J, et al.
Science . 2017 Oct; 358(6366):1019-1027. PMID: 29070703
Nucleic acid editing holds promise for treating genetic disease, particularly at the RNA level, where disease-relevant sequences can be rescued to yield functional protein products. Type VI CRISPR-Cas systems contain...
20.
Abudayyeh O, Gootenberg J, Essletzbichler P, Han S, Joung J, Belanto J, et al.
Nature . 2017 Oct; 550(7675):280-284. PMID: 28976959
RNA has important and diverse roles in biology, but molecular tools to manipulate and measure it are limited. For example, RNA interference can efficiently knockdown RNAs, but it is prone...