Julia C Liu
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Explore the profile of Julia C Liu including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
804
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Recent Articles
1.
Ozkurede U, Pakkiriswami S, Liu J
Trends Pharmacol Sci
. 2024 Oct;
45(11):950-952.
PMID: 39406593
Regulation of mitochondrial calcium uptake by the mitochondrial calcium uniporter (mtCU) complex is crucial for heart function. In a recent study, Hasan et al. demonstrated that mitochondrial calcium uptake (MICU)1...
2.
Roman B, Mastoor Y, Sun J, Chapoy Villanueva H, Hinojosa G, Springer D, et al.
Circ Res
. 2024 May;
135(1):26-40.
PMID: 38747181
Background: Calcium (Ca) uptake by mitochondria occurs via the mitochondrial Ca uniporter. Mitochondrial Ca uniporter exists as a complex, regulated by 3 MICU (mitochondrial Ca uptake) proteins localized in the...
3.
Stevens J, Dobratz T, Fischer K, Palmer A, Bourdage K, Wong A, et al.
Am J Physiol Heart Circ Physiol
. 2023 Dec;
326(2):H396-H407.
PMID: 38099842
Heart disease is a leading cause of death in patients with Duchenne muscular dystrophy (DMD), characterized by the progressive replacement of contractile tissue with scar tissue. Effective therapies for dystrophic...
4.
Sung J, Chapoy Villanueva H, Feng F, Araque Igualador A, Prins K, Liu J
J Mol Cell Cardiol
. 2023 Jul;
182:54-56.
PMID: 37454413
No abstract available.
5.
Chapoy Villanueva H, Sung J, Stevens J, Zhang M, Nelson P, Denduluri L, et al.
J Mol Cell Cardiol
. 2023 May;
181:33-45.
PMID: 37230379
Transport of Ca into mitochondria is thought to stimulate the production of ATP, a critical process in the heart's fight or flight response, but excess Ca can trigger cell death....
6.
Murphy E, Liu J
Cardiovasc Res
. 2022 Aug;
119(5):1105-1116.
PMID: 35986915
Cardiomyocytes are one of the most mitochondria-rich cell types in the body, with ∼30-40% of the cell volume being composed of mitochondria. Mitochondria are well established as the primary site...
7.
Puente B, Sun J, Parks R, Fergusson M, Liu C, Springer D, et al.
Circ Res
. 2020 Oct;
127(12):1571-1573.
PMID: 33059536
No abstract available.
8.
Liu J
J Mol Cell Cardiol
. 2020 May;
143:175-183.
PMID: 32389793
The uptake of Ca into mitochondria is thought to be an important signal communicating the need for increased energy production. However, dysregulated uptake leading to mitochondrial Ca overload can trigger...
9.
Liu J, Syder N, Ghorashi N, Willingham T, Parks R, Sun J, et al.
JCI Insight
. 2020 Feb;
5(4).
PMID: 32017711
The mitochondrial calcium uniporter is widely accepted as the primary route of rapid calcium entry into mitochondria, where increases in matrix calcium contribute to bioenergetics but also mitochondrial permeability and...
10.
Parks R, Murphy E, Liu J
Methods Mol Biol
. 2018 Jun;
1782:187-196.
PMID: 29851001
The opening of a large conductance channel in the inner mitochondrial membrane, known as the mitochondrial permeability transition pore (PTP), has been shown to be a primary mediator of cell...