Juan R Cubillos-Ruiz
Overview
Explore the profile of Juan R Cubillos-Ruiz including associated specialties, affiliations and a list of published articles.
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67
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7300
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Recent Articles
1.
Hwang S, Awasthi D, Jeong J, Sandoval T, Chae C, Ramos Y, et al.
Nature
. 2024 Oct;
635(8040):1010-1018.
PMID: 39443795
Mounting effective immunity against pathogens and tumours relies on the successful metabolic programming of T cells by extracellular fatty acids. Fatty-acid-binding protein 5 (FABP5) has a key role in this...
2.
Madani W, Ramos Y, Cubillos-Ruiz J, Morales D
FEMS Microbes
. 2024 Oct;
5:xtae027.
PMID: 39391373
The gastrointestinal tract (GIT) is typically considered the natural niche of enterococci. However, these bacteria also inhabit extraintestinal tissues, where they can disrupt organ physiology and cause life-threatening infections. Here,...
3.
Emmanuelli A, Salvagno C, Hwang S, Awasthi D, Sandoval T, Chae C, et al.
Oncoimmunology
. 2024 Oct;
13(1):2411070.
PMID: 39364290
High-grade serious ovarian cancer (HGSOC) is an aggressive malignancy that remains refractory to current immunotherapies. While advanced stage disease has been extensively studied, the cellular and molecular mechanisms that promote...
4.
Markowitz G, Ban Y, Tavarez D, Yoffe L, Podaza E, He Y, et al.
Nat Immunol
. 2024 Sep;
25(10):1884-1899.
PMID: 39327500
TCF1 progenitor CD8 T cells mediate the efficacy of immunotherapy; however, the mechanisms that govern their generation and maintenance are poorly understood. Here, we show that targeting glycolysis through deletion...
5.
Emmanuelli A, Salvagno C, Min-Hwang S, Awasthi D, Sandoval T, Chae C, et al.
bioRxiv
. 2024 Aug;
PMID: 39211073
High-grade serous ovarian cancer (HGSOC) is an aggressive malignancy that remains refractory to current immunotherapies. While advanced stage disease has been extensively studied, the cellular and molecular mechanisms that promote...
6.
Sandoval T, Salvagno C, Chae C, Awasthi D, Giovanelli P, Marin Falco M, et al.
Cancer Discov
. 2024 Jul;
14(10):1901-1921.
PMID: 39073085
Iron accumulation in tumors contributes to disease progression and chemoresistance. Although targeting this process can influence various hallmarks of cancer, the immunomodulatory effects of iron chelation in the tumor microenvironment...
7.
Hwang S, Awasthi D, Jeong J, Sandoval T, Chae C, Ramos Y, et al.
Res Sq
. 2024 Jan;
PMID: 38168227
Mounting effective immunity against pathogens and tumors relies on the successful metabolic programming of T cells by extracellular fatty acids. During this process, fatty-acid-binding protein 5 (FABP5) imports lipids that...
8.
Fernandez J, Mancebo C, Garcinuno S, March G, Alvarez Y, Alonso S, et al.
Genes Immun
. 2023 Dec;
25(1):43-54.
PMID: 38146001
The utilization of host-cell machinery during SARS-CoV-2 infection can overwhelm the protein-folding capacity of the endoplasmic reticulum and activate the unfolded protein response (UPR). The IRE1α-XBP1 arm of the UPR...
9.
Smolgovsky S, Bayer A, Kaur K, Sanders E, Aronovitz M, Filipp M, et al.
J Clin Invest
. 2023 Oct;
133(24).
PMID: 37874641
Heart failure with preserved ejection fraction (HFpEF) is a widespread syndrome with limited therapeutic options and poorly understood immune pathophysiology. Using a 2-hit preclinical model of cardiometabolic HFpEF that induces...
10.
Markowitz G, Ban Y, Tavarez D, Yoffe L, Podaza E, He Y, et al.
Res Sq
. 2023 Oct;
PMID: 37790365
TCF1 progenitor CD8+ T cells mediate the efficacy of PD-1 blockade, however the mechanisms that govern their generation and maintenance are poorly understood. Here, we show that targeting glycolysis through...