Juan Carlos Lopez-Rodriguez
Overview
Explore the profile of Juan Carlos Lopez-Rodriguez including associated specialties, affiliations and a list of published articles.
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8
Citations
52
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Recent Articles
1.
Lopez-Rodriguez J, Hancock S, Li K, Crotta S, Barrington C, Suarez-Bonnet A, et al.
J Exp Med
. 2023 Jul;
220(10).
PMID: 37516912
Mucosal-associated invariant T (MAIT) cells are abundant in the lung and contribute to host defense against infections. During bacterial infections, MAIT cell activation has been proposed to require T cell...
2.
Parron-Ballesteros J, Gordo R, Lopez-Rodriguez J, Olmo N, Villalba M, Batanero E, et al.
Front Allergy
. 2023 Feb;
4:1093800.
PMID: 36793545
The "epithelial barrier hypothesis" states that a barrier dysfunction can result in allergy development due to tolerance breakdown. This barrier alteration may come from the direct contact of epithelial and...
3.
Brailey P, Evans L, Lopez-Rodriguez J, Sinadinos A, Tyrrel V, Kelly G, et al.
Nat Commun
. 2022 Nov;
13(1):6723.
PMID: 36344546
Alterations in cellular metabolism underpin macrophage activation, yet little is known regarding how key immunological molecules regulate metabolic programs in macrophages. Here we uncover a function for the antigen presenting...
4.
Lopez-Rodriguez J, Rodriguez-Coira J, Benede S, Barbas C, Barber D, Villalba M, et al.
Clin Transl Allergy
. 2021 Sep;
11(7):e12051.
PMID: 34582104
Background: Several studies have shown a correlation between an altered metabolome and respiratory allergies. The epithelial barrier hypothesis proposes that an epithelial barrier dysfunction can result in allergic diseases development....
5.
Lazaro-Gorines R, Lopez-Rodriguez J, Benede S, Gonzalez M, Mayorga C, Vogel L, et al.
Sci Rep
. 2020 Jul;
10(1):12255.
PMID: 32703972
Immunotoxins appear as promising therapeutic molecules, alternative to allergen-specific-immunotherapy. In this work, we achieved the development of a protein chimera able to promote specific cell death on effector cells involved...
6.
Oeo-Santos C, Lopez-Rodriguez J, Garcia-Mouton C, San Segundo-Acosta P, Jurado A, Moreno-Aguilar C, et al.
Biochim Biophys Acta Biomembr
. 2020 Mar;
1862(6):183258.
PMID: 32142819
Ole e 7 allergen from Olea europaea pollen possesses a major clinical relevance because it produces severe symptoms, such as anaphylaxis, in allergic patients exposed to high olive pollen counts....
7.
Benede S, Ramos-Soriano J, Palomares F, Losada J, Mascaraque A, Lopez-Rodriguez J, et al.
Mol Pharm
. 2020 Jan;
17(3):827-836.
PMID: 31990560
Olive pollen is one of the most important causes of respiratory allergy, with Ole e 1 being the most clinically relevant sensitizing allergen. Peptide-based vaccines represent promising therapeutic approaches, but...
8.
Lopez-Rodriguez J, Manosalva J, Cabrera-Garcia J, Escribese M, Villalba M, Barber D, et al.
Redox Biol
. 2019 Jun;
26:101256.
PMID: 31229842
Environmental proteases have been widely associated to the pathogenesis of allergic disorders. Der p 1, a cysteine-protease from house dust mite (HDM) Dermatophagoides pteronyssinus, constitutes one of the most clinically...