Juan C Fontecilla-Camps
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Explore the profile of Juan C Fontecilla-Camps including associated specialties, affiliations and a list of published articles.
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91
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2472
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Recent Articles
1.
Gray E, Stewart M, Hanwell L, Crack J, Devine R, Stevenson C, et al.
Chem Sci
. 2023 Sep;
14(36):9744-9758.
PMID: 37736639
RirA is a global iron regulator in diverse that belongs to the Rrf2 superfamily of transcriptional regulators, which can contain an iron-sulfur (Fe-S) cluster. Under iron-replete conditions, RirA contains a...
2.
Fontecilla-Camps J
Chembiochem
. 2023 Apr;
24(10):e202300048.
PMID: 37052530
Examination of the genetic code (GeCo) reveals that amino acids coded by (A/U) codons display a large functional spectrum and bind RNA whereas, except for Arg, those coded by (G/C)...
3.
Rohac R, Crack J, de Rosny E, Gigarel O, Le Brun N, Fontecilla-Camps J, et al.
Commun Biol
. 2022 Jul;
5(1):769.
PMID: 35908109
Several transcription factors of the Rrf2 family use an iron-sulfur cluster to regulate DNA binding through effectors such as nitric oxide (NO), cellular redox status and iron levels. [4Fe-4S]-NsrR from...
4.
Fontecilla-Camps J, Volbeda A
Chem Rev
. 2022 May;
122(14):12110-12131.
PMID: 35536891
The activation energy barrier of biochemical reactions is normally lowered by an enzyme catalyst, which directly helps the weakening of the bond(s) to be broken. In many metalloenzymes, this is...
5.
Fontecilla-Camps J
Chembiochem
. 2022 Mar;
23(10):e202200064.
PMID: 35353443
ATP is generally defined as the "energy currency" of the cell. Its phosphoanhydride P-O bonds are often considered to be "high energy" linkages that release free energy when broken, and...
6.
Cherrier M, Vernede X, Fenel D, Martin L, Arragain B, Neumann E, et al.
Biomolecules
. 2022 Mar;
12(3).
PMID: 35327633
Metalloproteins are involved in key cell processes such as photosynthesis, respiration, and oxygen transport. However, the presence of transition metals (notably iron as a component of [Fe-S] clusters) often makes...
7.
Fontecilla-Camps J
Metallomics
. 2022 Mar;
14(4).
PMID: 35294026
Although nickel (Ni) is a minor element of the Earth's crust, it has played a major role in the evolution of life. This metal is a component of the active...
8.
Basbous H, Volbeda A, Amara P, Rohac R, Martin L, de Choudens S, et al.
ACS Chem Biol
. 2021 Oct;
16(11):2423-2433.
PMID: 34609124
Quinolinate synthase, also called NadA, is a [4Fe-4S]-containing enzyme that uses what is probably the oldest pathway to generate quinolinic acid (QA), the universal precursor of the biologically essential cofactor...
9.
Fontecilla-Camps J
J Inorg Biochem
. 2021 Jan;
216:111347.
PMID: 33450675
Life requires energy to exist, to reproduce and to survive. Two major hypotheses have been put forward concerning the source of this energy at the very early stages of life...
10.
Crack J, Amara P, Volbeda A, Mouesca J, Rohac R, Pellicer Martinez M, et al.
J Am Chem Soc
. 2020 Feb;
142(11):5104-5116.
PMID: 32078310
The [FeS]-RsrR gene transcription regulator senses the redox status in bacteria by modulating DNA binding, while its cluster cycles between +1 and +2 states-only the latter binds DNA. We have...