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Juan A Marchal

Explore the profile of Juan A Marchal including associated specialties, affiliations and a list of published articles. Areas
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Articles 90
Citations 1150
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Recent Articles
1.
Justicia-Lirio P, Tristan-Manzano M, Maldonado-Perez N, Barbero-Jimenez C, Cortijo-Gutierrez M, Pavlovic K, et al.
Mol Ther Nucleic Acids . 2024 Dec; 35(4):102308. PMID: 39640015
Although chimeric antigen receptor (CAR) T cell therapy has revolutionized type B cancer treatment, efficacy remains limited in various lymphomas and solid tumors. Reinforcing conventional CAR-T cells to release cytokines...
2.
Perez-Lloret M, Reidy E, Lozano-Perez A, Marchal J, Lens P, Ryan A, et al.
Drug Deliv Transl Res . 2024 Oct; PMID: 39382824
Colorectal cancer (CRC) is the second most common cause of cancer related deaths worldwide and the prevalence in young people especially is increasing annually. In the search for innovative approaches...
3.
Ramos M, Crespo-Sueiro G, de Pedro N, Grinan-Lison C, Diaz C, Perez-Victoria I, et al.
Biomed Pharmacother . 2024 Jun; 177:117018. PMID: 38908208
Pancreatic cancer (PC) shows a high fatality rate that can only be faced with a combination of surgery and chemotherapy or palliative treatment in the case of advanced patients. Besides,...
4.
Blaya-Canovas J, Grinan-Lison C, Blancas I, Marchal J, Ramirez-Tortosa C, Lopez-Tejada A, et al.
Mol Cancer . 2024 May; 23(1):83. PMID: 38730475
Background: Active targeting by surface-modified nanoplatforms enables a more precise and elevated accumulation of nanoparticles within the tumor, thereby enhancing drug delivery and efficacy for a successful cancer treatment. However,...
5.
Galocha-Leon C, Antich C, Voltes-Martinez A, Marchal J, Mallandrich M, Halbaut L, et al.
Drug Deliv Transl Res . 2024 Apr; 15(1):291-311. PMID: 38662335
Three-dimensional (3D) bioprinting is considered one of the most advanced tools to build up materials for tissue engineering. The aim of this work was the design, development and characterization of...
6.
Calahorra J, Blaya-Canovas J, Castellini-Perez O, Aparicio-Puerta E, Cives-Losada C, Marin J, et al.
Biomed Pharmacother . 2024 Mar; 174:116439. PMID: 38518601
Triple-negative breast cancer (TNBC) is characterised by its aggressiveness and resistance to chemotherapy, demanding the development of effective strategies against its unique characteristics. Derived from lapacho tree bark, β-lapachone (β-LP)...
7.
Gravan P, Pena-Martin J, Andres J, Pedrosa M, Villegas-Montoya M, Galisteo-Gonzalez F, et al.
ACS Appl Mater Interfaces . 2023 Dec; 16(2):2058-2074. PMID: 38159050
Nanotechnological platforms offer advantages over conventional therapeutic and diagnostic modalities. However, the efficient biointerfacing of nanomaterials for biomedical applications remains challenging. In recent years, nanoparticles (NPs) with different coatings have...
8.
Galocha-Leon C, Antich C, Voltes-Martinez A, Marchal J, Mallandrich M, Halbaut L, et al.
Int J Pharm . 2023 Oct; 647:123535. PMID: 37865132
Wound healing is a natural physiological reaction to tissue injury. Hydrogels show attractive advantages in wound healing not only due to their biodegradability, biocompatibility and permeability but also because provide...
9.
Garcia-Ortega M, Aparicio E, Grinan-Lison C, Jimenez G, Lopez-Ruiz E, Palacios J, et al.
Cancers (Basel) . 2023 Jul; 15(14). PMID: 37509327
Malignant melanoma (MM) can spread to other organs and is resistant in part due to the presence of cancer stem cell subpopulations (CSCs). While a controversial high dose of interferon-alpha...
10.
Valverde-Pozo J, Paredes J, Widmann T, Grinan-Lison C, Ceccarelli G, Gioiello A, et al.
ACS Sens . 2023 Feb; 8(3):1064-1075. PMID: 36847549
DPP IV, otherwise known as CD26 lymphocyte T surface antigen, is a transmembrane glycoprotein also found in circulation in the blood. It plays an important role in several processes like...