Juan-Jose Vasquez
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Explore the profile of Juan-Jose Vasquez including associated specialties, affiliations and a list of published articles.
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5
Citations
185
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Recent Articles
1.
Bifeld E, Lorenzen S, Bartsch K, Vasquez J, Siegel T, Clos J
mSystems
. 2018 Dec;
3(6).
PMID: 30505948
The 90-kDa heat shock protein (HSP90) of eukaryotes is a highly abundant and essential chaperone required for the maturation of regulatory and signal proteins. In the protozoan parasite Leishmania donovani,...
2.
Vasquez J, Wedel C, Cosentino R, Siegel T
Nucleic Acids Res
. 2018 Jun;
46(18):e106.
PMID: 29912461
Despite their importance for most DNA-templated processes, the function of individual histone modifications has remained largely unknown because in vivo mutational analyses are lacking. The reason for this is that...
3.
Vasquez J, Hon C, Vanselow J, Schlosser A, Siegel T
Nucleic Acids Res
. 2014 Jan;
42(6):3623-37.
PMID: 24442674
While gene expression is a fundamental and tightly controlled cellular process that is regulated at multiple steps, the exact contribution of each step remains unknown in any organism. The absence...
4.
Walker J, Gongora R, Vasquez J, Drummelsmith J, Burchmore R, Roy G, et al.
Mol Biochem Parasitol
. 2012 Mar;
183(2):166-76.
PMID: 22449941
The rate of treatment failure to antileishmanial chemotherapy in Latin America is up to 64%. Parasite drug resistance contributes to an unknown proportion of treatment failures. Identification of clinically relevant...
5.
Walker J, Vasquez J, Gomez M, Drummelsmith J, Burchmore R, Girard I, et al.
Mol Biochem Parasitol
. 2006 Mar;
147(1):64-73.
PMID: 16530278
We have employed proteomics to identify proteins upregulated in the amastigote life-stage of Leishmaniapanamensis, using axenically-differentiated forms as models of authentic intracellular parasites. Resolution of the soluble proteomes of axenic...