Stephan Lorenzen
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Explore the profile of Stephan Lorenzen including associated specialties, affiliations and a list of published articles.
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44
Citations
742
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Recent Articles
1.
Grunebast J, Lorenzen S, Clos J
mBio
. 2024 Nov;
16(1):e0224124.
PMID: 39584812
is a human-pathogenic, obligate parasite and the etiological agent of the most prevalent, cutaneous form of leishmaniasis, which is an important neglected, tropical disease with ~1.2 million new infections per...
2.
Bonde A, Lorenzen S, Brixen G, Troelsen A, Sillesen M
Front Digit Health
. 2024 Jan;
5:1249835.
PMID: 38259257
Background: High-quality outcomes data is crucial for continued surgical quality improvement. Outcomes are generally captured through structured administrative data or through manual curation of unstructured electronic health record (EHR) data....
3.
Anders J, Konig C, Lender C, Hellhund A, Nehls S, Shalabi I, et al.
PLoS Pathog
. 2023 Dec;
19(12):e1011745.
PMID: 38134215
Recently, two genes involved in amoebic liver abscess formation in a mouse model were identified by their differential expression of non-pathogenic (A1np) and pathogenic (B2p) clones of the Entamoeba histolytica...
4.
Raacke M, Kerr A, Dorpinghaus M, Brehmer J, Wu Y, Lorenzen S, et al.
Cells
. 2021 Aug;
10(7).
PMID: 34359826
Infections with the deadliest malaria parasite, , are accompanied by a strong immunological response of the human host. To date, more than 30 cytokines have been detected in elevated levels...
5.
Wu Y, Bouws P, Lorenzen S, Bruchhaus I, Metwally N
Methods Mol Biol
. 2021 Jul;
2369:187-197.
PMID: 34313990
During malaria infection, the endothelial lining of the small blood vessels of the brain and other vital organs is strongly stimulated. This leads to fatal complications and poor prognosis of...
6.
Grunebast J, Lorenzen S, Zummack J, Clos J
mSystems
. 2021 Jul;
6(4):e0062821.
PMID: 34282941
Leishmania donovani is a parasitic protist that causes the lethal Kala-azar fever in India and East Africa. Gene expression in is regulated by gene copy number variation and inducible translation...
7.
Droge L, Hennies S, Lorenzen S, Conradi L, Quack H, Liersch T, et al.
BMC Cancer
. 2021 Mar;
21(1):219.
PMID: 33663399
Background: The question whether lymphocyte radiosensitivity is representative of patients' response to radiotherapy (RT) remains unsolved. We analyzed lymphocyte cytogenetic damage in patients who were homogeneously treated with preoperative radiochemotherapy...
8.
Jimenez-Solem E, Petersen T, Hansen C, Hansen C, Lioma C, Igel C, et al.
Sci Rep
. 2021 Feb;
11(1):3246.
PMID: 33547335
Patients with severe COVID-19 have overwhelmed healthcare systems worldwide. We hypothesized that machine learning (ML) models could be used to predict risks at different stages of management and thereby provide...
9.
Maier B, Lorenzen S, Finger A, Herzel H, Kramer A
Methods Mol Biol
. 2020 Dec;
2130:103-114.
PMID: 33284439
RNA interference (RNAi) allows for the selective downregulation of gene expression by neutralizing targeted mRNA molecules and has frequently been used in high-throughput screening endeavors. Here, we describe a protocol...
10.
Krober-Boncardo C, Lorenzen S, Brinker C, Clos J
Sci Rep
. 2020 Sep;
10(1):15969.
PMID: 32994468
Leishmania donovani is a trypanosomatidic parasite and causes the lethal kala-azar fever, a neglected tropical disease. The Trypanosomatida are devoid of transcriptional gene regulation and rely on gene copy number...