Jolyne Drummelsmith
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Explore the profile of Jolyne Drummelsmith including associated specialties, affiliations and a list of published articles.
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13
Citations
499
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Recent Articles
1.
Walker J, Gongora R, Vasquez J, Drummelsmith J, Burchmore R, Roy G, et al.
Mol Biochem Parasitol
. 2012 Mar;
183(2):166-76.
PMID: 22449941
The rate of treatment failure to antileishmanial chemotherapy in Latin America is up to 64%. Parasite drug resistance contributes to an unknown proportion of treatment failures. Identification of clinically relevant...
2.
Brotherton M, Racine G, Foucher A, Drummelsmith J, Papadopoulou B, Ouellette M
J Proteome Res
. 2010 Jun;
9(8):3842-53.
PMID: 20583757
Prior analyses of the proteome of the protozoan parasite Leishmania have underrepresented basic proteins. Here, we applied protein fractionation by isoelectric point (pI) using free-flow electrophoresis (FFE) to study stage-specific...
3.
El Fadili K, Drummelsmith J, Roy G, Jardim A, Ouellette M
Exp Parasitol
. 2009 Jun;
123(1):51-7.
PMID: 19500579
The therapeutic mainstay against the protozoan parasite Leishmania is still based on the antiquated pentavalent antimonials, but resistance is increasing in several parts of the world. Resistance is now partly...
4.
Drummelsmith J, Winstall E, Bergeron M, Poirier G, Ouellette M
J Proteome Res
. 2007 Nov;
6(12):4690-702.
PMID: 17997515
Vancomycin-intermediate Staphylococcus aureus (VISA) strains tend to develop during glycopeptide treatment of infections caused by methicillin-resistant S. aureus (MRSA). Rapid and effective detection methods for VISA strains are lacking, and...
5.
Vergnes B, Gourbal B, Girard I, Sundar S, Drummelsmith J, Ouellette M
Mol Cell Proteomics
. 2006 Oct;
6(1):88-101.
PMID: 17050524
The therapeutic mainstay against the protozoan parasite Leishmania is still based on the antiquated pentavalent antimonials (Sb(V)), but resistance is increasing in several parts of the world. Resistance is now...
6.
McNicoll F, Drummelsmith J, Muller M, Madore E, Boilard N, Ouellette M, et al.
Proteomics
. 2006 May;
6(12):3567-81.
PMID: 16705753
Protozoan parasites of the genus Leishmania are found as promastigotes in the sandfly vector and as amastigotes in mammalian macrophages. Mechanisms controlling stage-regulated gene expression in these organisms are poorly...
7.
Walker J, Vasquez J, Gomez M, Drummelsmith J, Burchmore R, Girard I, et al.
Mol Biochem Parasitol
. 2006 Mar;
147(1):64-73.
PMID: 16530278
We have employed proteomics to identify proteins upregulated in the amastigote life-stage of Leishmaniapanamensis, using axenically-differentiated forms as models of authentic intracellular parasites. Resolution of the soluble proteomes of axenic...
8.
Soualhine H, Brochu V, Menard F, Papadopoulou B, Weiss K, Bergeron M, et al.
Mol Microbiol
. 2005 Nov;
58(5):1430-40.
PMID: 16313627
Resistance to penicillin is widespread in the Gram-positive bacterium Streptococcus pneumoniae, and while several mutations are known to be implicated in resistance other mechanisms are likely to occur. We used...
9.
Ouellette M, Drummelsmith J, Papadopoulou B
Drug Resist Updat
. 2004 Nov;
7(4-5):257-66.
PMID: 15533763
The control of Leishmania infections relies primarily on chemotherapy. The arsenal of drugs available for treating Leishmania infections is limited and includes pentavalent antimonials, pentamidine, amphotericin B, miltefosine, fluconazole and...
10.
Richard D, Leprohon P, Drummelsmith J, Ouellette M
J Biol Chem
. 2004 Oct;
279(52):54494-501.
PMID: 15466466
The protozoan parasite Leishmania relies on the uptake of folate and pterin from the environment to meet its nutritional requirements. We show here that a novel gene (folate transporter 1...