Joshua T Jones
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Explore the profile of Joshua T Jones including associated specialties, affiliations and a list of published articles.
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10
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1896
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Recent Articles
1.
Eguchi T, Kadota K, Chaft J, Evans B, Kidd J, Tan K, et al.
Oncotarget
. 2016 May;
7(23):35241-56.
PMID: 27153551
Purpose: The goals of our study were (a) to validate a molecular expression signature (cell cycle progression [CCP] score and molecular prognostic score [mPS; combination of CCP and pathological stage...
2.
Telli M, Timms K, Reid J, Hennessy B, Mills G, Jensen K, et al.
Clin Cancer Res
. 2016 Mar;
22(15):3764-73.
PMID: 26957554
Purpose: BRCA1/2-mutated and some sporadic triple-negative breast cancers (TNBC) have DNA repair defects and are sensitive to DNA-damaging therapeutics. Recently, three independent DNA-based measures of genomic instability were developed on...
3.
Bueno R, Hughes E, Wagner S, Gutin A, Lanchbury J, Zheng Y, et al.
J Thorac Oncol
. 2014 Nov;
10(1):67-73.
PMID: 25396679
Introduction: The aim of this study was to validate a molecular expression signature [cell cycle progression (CCP) score] that identifies patients with a higher risk of cancer-related death after surgical...
4.
Hahn A, Jones J, Meyer T
Cell Cycle
. 2009 Mar;
8(7):1044-52.
PMID: 19270522
Cell cycle analysis typically relies on fixed time-point measurements of cells in particular phases of the cell cycle. The cell cycle, however, is a dynamic process whose subtle shifts are...
5.
Burney R, Lee A, Leong D, Jones J, Hahn A, Meyer T, et al.
Cell Cycle
. 2007 Sep;
6(18):2276-83.
PMID: 17881898
High content cell-based genetic and small molecule library screens are powerful strategies in drug discovery and investigations of disease mechanisms. We report that primary cells derived from a transgenic mouse...
6.
Galvez T, Teruel M, Heo W, Jones J, Kim M, Liou J, et al.
Genome Biol
. 2007 Jul;
8(7):R142.
PMID: 17640392
Background: Iron uptake via endocytosis of iron-transferrin-transferrin receptor complexes is a rate-limiting step for cell growth, viability and proliferation in tumor cells as well as non-transformed cells such as activated...
7.
Gong D, Pomerening J, Myers J, Gustavsson C, Jones J, Hahn A, et al.
Curr Biol
. 2007 Jan;
17(1):85-91.
PMID: 17208191
Mitosis is thought to be triggered by the activation of Cdk-cyclin complexes. Here we have used RNA interference (RNAi) to assess the roles of three mitotic cyclins, cyclins A2, B1,...
8.
Liou J, Kim M, Heo W, Jones J, Myers J, Ferrell Jr J, et al.
Curr Biol
. 2005 Jul;
15(13):1235-41.
PMID: 16005298
Ca(2+) signaling in nonexcitable cells is typically initiated by receptor-triggered production of inositol-1,4,5-trisphosphate and the release of Ca(2+) from intracellular stores. An elusive signaling process senses the Ca(2+) store depletion...
9.
Jones J, Myers J, Ferrell J, Meyer T
Nat Biotechnol
. 2004 Mar;
22(3):306-12.
PMID: 14990952
Precise timing of mitosis is essential for high-fidelity cell duplication. However, temporal measurements of the mitotic clock have been challenging. Here we present a fluorescent mitosis biosensor that monitors the...
10.
Myers J, Jones J, Meyer T, Ferrell Jr J
Nat Biotechnol
. 2003 Feb;
21(3):324-8.
PMID: 12592410
RNA interference (RNAi) is a powerful method for specifically silencing gene expression in diverse cell types. RNAi is mediated by approximately 21-nucleotide small interfering RNAs (siRNAs), which are produced from...