Joshua H Choe
Overview
Explore the profile of Joshua H Choe including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
151
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0
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Recent Articles
1.
Choe J, Kawase T, Xu A, Guzman A, Obradovic A, Low-Calle A, et al.
Cancer Discov
. 2023 Apr;
13(5):1250-1273.
PMID: 37067901
Significance: A mutant p53 (A347D), which can only form dimers, is associated with increased cancer susceptibility in LFS individuals. We found that this mutant wields a double-edged sword, driving tumorigenesis...
2.
Choe J, Mazambani S, Kim T, Kim J
Cells
. 2021 Apr;
10(3).
PMID: 33803326
Squamous cell carcinomas (SCCs) arise from both stratified squamous and non-squamous epithelium of diverse anatomical sites and collectively represent one of the most frequent solid tumors, accounting for more than...
3.
Hsieh M, Choe J, Gadhvi J, Kim Y, Arguez M, Palmer M, et al.
Cell Rep
. 2019 Aug;
28(7):1860-1878.e9.
PMID: 31412252
Squamous cell carcinoma (SCC), a malignancy arising across multiple anatomical sites, is responsible for significant cancer mortality due to insufficient therapeutic options. Here, we identify exceptional glucose reliance among SCCs...
4.
Katz C, Low-Calle A, Choe J, Laptenko O, Tong D, Joseph-Chowdhury J, et al.
Genes Dev
. 2018 Mar;
32(5-6):430-447.
PMID: 29549180
The p53 tumor suppressor protein is the most well studied as a regulator of transcription in the nucleus, where it exists primarily as a tetramer. However, there are other oligomeric...
5.
Goodwin J, Neugent M, Lee S, Choe J, Choi H, Jenkins D, et al.
Nat Commun
. 2017 May;
8:15503.
PMID: 28548087
Adenocarcinoma (ADC) and squamous cell carcinoma (SqCC) are the two predominant subtypes of non-small cell lung cancer (NSCLC) and are distinct in their histological, molecular and clinical presentation. However, metabolic...