Josh T Cuperus
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Explore the profile of Josh T Cuperus including associated specialties, affiliations and a list of published articles.
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37
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1910
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Recent Articles
11.
Zhang J, Greenwood N, Hernandez J, Cuperus J, Huang B, Ryder B, et al.
bioRxiv
. 2023 Oct;
PMID: 37781598
Protein quality control (PQC) is carried out in part by the chaperone Hsp70, in concert with adapters of the J-domain protein (JDP) family. The JDPs, also called Hsp40s, are thought...
12.
Gorjifard S, Jores T, Tonnies J, Mueth N, Bubb K, Wrightsman T, et al.
bioRxiv
. 2023 Jul;
PMID: 37398426
The 3' end of a gene, often called a terminator, modulates mRNA stability, localization, translation, and polyadenylation. Here, we adapted Plant STARR-seq, a massively parallel reporter assay, to measure the...
13.
Jores T, Hamm M, Cuperus J, Queitsch C
Curr Opin Plant Biol
. 2023 Jun;
75:102403.
PMID: 37331209
Understanding plant gene regulation has been a priority for generations of plant scientists. However, due to its complex nature, the regulatory code governing plant gene expression has yet to be...
14.
Alexandre C, Bubb K, Schultz K, Lempe J, Cuperus J, Queitsch C
bioRxiv
. 2023 May;
PMID: 37214854
Isogenic individuals can display seemingly stochastic phenotypic differences, limiting the accuracy of genotype-to-phenotype predictions. The extent of this phenotypic variation depends in part on genetic background, raising questions about the...
15.
Morton E, Hall A, Cuperus J, Queitsch C
Genetics
. 2023 Mar;
224(1).
PMID: 36919976
The genes that encode ribosomal RNAs are present in several hundred copies in most eukaryotes. These vast arrays of repetitive ribosomal DNA (rDNA) have been implicated not just in ribosome...
16.
Kwan E, Alvino G, Lynch K, Levan P, Amemiya H, Wang X, et al.
Cell Rep
. 2023 Feb;
42(3):112161.
PMID: 36842087
Timely completion of genome replication is a prerequisite for mitosis, genome integrity, and cell survival. A challenge to this timely completion comes from the need to replicate the hundreds of...
17.
Lemus T, Mason G, Bubb K, Alexandre C, Queitsch C, Cuperus J
Genetics
. 2022 Oct;
223(2).
PMID: 36303325
Argonaute 1 (AGO1), the principal protein component of microRNA-mediated regulation, plays a key role in plant growth and development. AGO1 physically interacts with the chaperone HSP90, which buffers cryptic genetic...
18.
Savinov A, Brandsen B, Angell B, Cuperus J, Fields S
Genome Biol
. 2021 Oct;
22(1):293.
PMID: 34663436
Background: The 3' untranslated region (UTR) plays critical roles in determining the level of gene expression through effects on activities such as mRNA stability and translation. Functional elements within this...
19.
Cuperus J
Plant Physiol
. 2021 Oct;
188(2):749-755.
PMID: 34662424
Single-cell genomics has the potential to revolutionize the study of plant development and tissue-specific responses to environmental stimuli by revealing heretofore unknown players and gene regulatory processes. Here, I focus...
20.
Dorrity M, Alexandre C, Hamm M, Vigil A, Fields S, Queitsch C, et al.
Nat Commun
. 2021 Jun;
12(1):3334.
PMID: 34099698
The scarcity of accessible sites that are dynamic or cell type-specific in plants may be due in part to tissue heterogeneity in bulk studies. To assess the effects of tissue...