Josh T Cuperus
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Explore the profile of Josh T Cuperus including associated specialties, affiliations and a list of published articles.
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37
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1910
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Recent Articles
21.
Jores T, Tonnies J, Wrightsman T, Buckler E, Cuperus J, Fields S, et al.
Nat Plants
. 2021 Jun;
7(6):842-855.
PMID: 34083762
Targeted engineering of plant gene expression holds great promise for ensuring food security and for producing biopharmaceuticals in plants. However, this engineering requires thorough knowledge of cis-regulatory elements to precisely...
22.
Gala H, Lanctot A, Jean-Baptiste K, Guiziou S, Chu J, Zemke J, et al.
Plant Cell
. 2021 Apr;
33(7):2197-2220.
PMID: 33822225
Root architecture is a major determinant of plant fitness and is under constant modification in response to favorable and unfavorable environmental stimuli. Beyond impacts on the primary root, the environment...
23.
Cuperus J, Queitsch C
Curr Opin Plant Biol
. 2020 Jun;
54:A1-A4.
PMID: 32553358
No abstract available.
24.
Jores T, Tonnies J, Dorrity M, Cuperus J, Fields S, Queitsch C
Plant Cell
. 2020 May;
32(7):2120-2131.
PMID: 32409318
Genetic engineering of -regulatory elements in crop plants is a promising strategy to ensure food security. However, such engineering is currently hindered by our limited knowledge of plant -regulatory elements....
25.
McFaline-Figueroa J, Trapnell C, Cuperus J
Curr Opin Plant Biol
. 2020 May;
54:114-121.
PMID: 32388018
Single-cell genomic approaches have the potential to revolutionize the study of plant systems. Here, we highlight newly developed techniques to analyze transcriptomes at single-cell resolution. We focus on the rigorous...
26.
Jean-Baptiste K, McFaline-Figueroa J, Alexandre C, Dorrity M, Saunders L, Bubb K, et al.
Plant Cell
. 2019 Mar;
31(5):993-1011.
PMID: 30923229
Single cell RNA sequencing can yield high-resolution cell-type-specific expression signatures that reveal new cell types and the developmental trajectories of cell lineages. Here, we apply this approach to Arabidopsis ()...
27.
Dorrity M, Cuperus J, Carlisle J, Fields S, Queitsch C
Proc Natl Acad Sci U S A
. 2018 Aug;
115(34):E7997-E8006.
PMID: 30068600
Few mechanisms are known that explain how transcription factors can adjust phenotypic outputs to accommodate differing environments. In , the decision to mate or invade relies on environmental cues that...
28.
Alexandre C, Urton J, Jean-Baptiste K, Huddleston J, Dorrity M, Cuperus J, et al.
Mol Biol Evol
. 2017 Dec;
35(4):837-854.
PMID: 29272536
Variation in regulatory DNA is thought to drive phenotypic variation, evolution, and disease. Prior studies of regulatory DNA and transcription factors across animal species highlighted a fundamental conundrum: Transcription factor...
29.
Cuperus J, Groves B, Kuchina A, Rosenberg A, Jojic N, Fields S, et al.
Genome Res
. 2017 Nov;
27(12):2015-2024.
PMID: 29097404
Our ability to predict protein expression from DNA sequence alone remains poor, reflecting our limited understanding of -regulatory grammar and hampering the design of engineered genes for synthetic biology applications....
30.
Cuperus J, Lo R, Shumaker L, Proctor J, Fields S
ACS Synth Biol
. 2015 Mar;
4(7):842-52.
PMID: 25742460
Strategies to optimize a metabolic pathway often involve building a large collection of strains, each containing different versions of sequences that regulate the expression of pathway genes. Here, we develop...