Josh Crouse
Overview
Explore the profile of Josh Crouse including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
738
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0
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Recent Articles
1.
Okoye I, Wang L, Pallmer K, Richter K, Ichimura T, Haas R, et al.
Science
. 2015 Apr;
348(6238):995-1001.
PMID: 25883318
Protective CD8(+) T cell-mediated immunity requires a massive expansion in cell number and the development of long-lived memory cells. Using forward genetics in mice, we identified an orphan protein named...
2.
Crouse J, Kalinke U, Oxenius A
Nat Rev Immunol
. 2015 Mar;
15(4):231-42.
PMID: 25790790
Type I interferons (IFNs) are pro-inflammatory cytokines that are rapidly induced in different cell types during viral infections. The consequences of type I IFN signalling include direct antiviral activity, innate...
3.
Crouse J, Xu H, Lang P, Oxenius A
Trends Immunol
. 2014 Nov;
36(1):49-58.
PMID: 25432489
Natural killer (NK) cells are important innate effectors in immunity. NK cells also have a role in the regulation of the adaptive immune response, and have been shown, in different...
4.
Crouse J, Bedenikovic G, Wiesel M, Ibberson M, Xenarios I, von Laer D, et al.
Immunity
. 2014 Jun;
40(6):961-73.
PMID: 24909889
Direct type I interferon (IFN) signaling on T cells is necessary for the proper expansion, differentiation, and survival of responding T cells following infection with viruses prominently inducing type I...
5.
Bedenikovic G, Crouse J, Oxenius A
Eur J Immunol
. 2013 Oct;
44(1):115-26.
PMID: 24108445
Due to their capacity to differentiate into long-lived memory cells, CD8(+) T cells are able to resolve subsequent infections faster than during the primary response. Among other factors, CD4(+) T...
6.
Wiesel M, Crouse J, Bedenikovic G, Sutherland A, Joller N, Oxenius A
Eur J Immunol
. 2011 Nov;
42(2):320-9.
PMID: 22102057
Two subsets of CD8(+) T cells are generated early during an immune response; one of these subsets forms the memory pool, known as memory precursor effector cells (MPECs), identified by...
7.
Wiesel M, Joller N, Ehlert A, Crouse J, Sporri R, Bachmann M, et al.
J Immunol
. 2010 Oct;
185(9):5188-97.
PMID: 20881183
The mechanisms of how Th cells promote CD8(+) T cell responses during viral infections are largely unknown. In this study, we unraveled the mechanisms of T cell help for CD8(+)...
8.
Mercer J, Knebel S, Schmidt F, Crouse J, Burkard C, Helenius A
Proc Natl Acad Sci U S A
. 2010 May;
107(20):9346-51.
PMID: 20439710
To enter host cells, vaccinia virus, a prototype poxvirus, can induce transient macropinocytosis followed by endocytic internalization and penetration through the limiting membrane of pinosomes by membrane fusion. Although mature...