Josephine Egan
Overview
Explore the profile of Josephine Egan including associated specialties, affiliations and a list of published articles.
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20
Citations
1486
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Recent Articles
1.
Choy C, Chen J, Li J, Gallagher D, Lu J, Wu D, et al.
Nat Commun
. 2023 Oct;
14(1):6725.
PMID: 37872153
The resolution of SARS-CoV-2 replication hinges on cell-mediated immunity, wherein CD8 T cells play a vital role. Nonetheless, the characterization of the specificity and TCR composition of CD8 T cells...
2.
Palliyaguru D, Shiroma E, Nam J, Duregon E, Teixeira C, Price N, et al.
Cell Metab
. 2021 Sep;
33(11):2189-2200.e3.
PMID: 34508697
Aging leads to profound changes in glucose homeostasis, weight, and adiposity, which are considered good predictors of health and survival in humans. Direct evidence that these age-associated metabolic alterations are...
3.
Lagou V, Magi R, Hottenga J, Grallert H, Perry J, Bouatia-Naji N, et al.
Nat Commun
. 2021 Feb;
12(1):995.
PMID: 33558525
No abstract available.
4.
Lagou V, Magi R, Hottenga J, Grallert H, Perry J, Bouatia-Naji N, et al.
Nat Commun
. 2021 Jan;
12(1):24.
PMID: 33402679
Differences between sexes contribute to variation in the levels of fasting glucose and insulin. Epidemiological studies established a higher prevalence of impaired fasting glucose in men and impaired glucose tolerance...
5.
Chaganti S, Mawn L, Kang H, Egan J, Resnick S, Beason-Held L, et al.
IEEE J Biomed Health Inform
. 2019 Jan;
23(5):2052-2062.
PMID: 30602428
Composite models that combine medical imaging with electronic medical records (EMR) improve predictive power when compared to traditional models that use imaging alone. The digitization of EMR provides potential access...
6.
Bodogai M, OConnell J, Kim K, Kim Y, Moritoh K, Chen C, et al.
Sci Transl Med
. 2018 Nov;
10(467).
PMID: 30429354
Aging in humans is associated with increased hyperglycemia and insulin resistance (collectively termed IR) and dysregulation of the immune system. However, the causative factors underlying their association remain unknown. Here,...
7.
Freeman D, Noren Hooten N, Eitan E, Green J, Mode N, Bodogai M, et al.
Diabetes
. 2018 May;
67(11):2377-2388.
PMID: 29720498
Type 2 diabetes is a chronic age-associated degenerative metabolic disease that reflects relative insulin deficiency and resistance. Extracellular vesicles (EVs) (exosomes, microvesicles, and apoptotic bodies) are small (30-400 nm) lipid-bound...
8.
Wheeler E, Leong A, Liu C, Hivert M, Strawbridge R, Podmore C, et al.
PLoS Med
. 2017 Sep;
14(9):e1002383.
PMID: 28898252
Background: Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic control in patients with diabetes. Previous genome-wide association studies (GWAS) have identified 18 HbA1c-associated genetic...
9.
Kalyani R, Metter E, Egan J, Golden S, Ferrucci L
Diabetes Care
. 2014 Nov;
38(1):82-90.
PMID: 25392294
Objective: Persons with diabetes have accelerated muscle loss compared with their counterparts. The relationship of hyperglycemia per se to declines in muscle function has not been explored yet has implications...
10.
Thambisetty M, Metter E, Yang A, Dolan H, Marano C, Zonderman A, et al.
JAMA Neurol
. 2013 Jul;
70(9):1167-72.
PMID: 23897112
Importance: Peripheral glucose homeostasis has been implicated in the pathogenesis of Alzheimer disease (AD). The relationship among diabetes mellitus, insulin, and AD is an important area of investigation. However, whether...