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David S Siscovick

Explore the profile of David S Siscovick including associated specialties, affiliations and a list of published articles. Areas
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Articles 498
Citations 33194
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Recent Articles
1.
Moseholm K, Jensen M, Buzkova P, Aroner S, Fitzpatrick A, Longstreth Jr W, et al.
Neurobiol Aging . 2025 Feb; 148:71-79. PMID: 39951847
Circulating non-esterified fatty acids (NEFAs) have toxic effects on a variety of organs central to cardiometabolic disease and can cross the blood-brain barrier. Whether NEFAs associate with cognitive decline or...
2.
Bhatia R, Hernandez M, Platt J, Newman A, Siscovick D, Mukamal K, et al.
BMJ Nutr Prev Health . 2025 Jan; 7(2):e000646. PMID: 39882284
Background: A healthier diet is associated with lower chronic disease burden, but the impact of neighbourhood food environments on disability and death in older adults is not known. Methods: In...
3.
Kim C, Appiah D, Yin Z, Schreiner P, Lewis C, McLaughlin M, et al.
medRxiv . 2025 Jan; PMID: 39830257
Introduction: Previous reports have noted associations between subfertility in women and increased risk of cardiovascular disease (CVD) events in later life. However, reports conflict regarding the associations between subfertility and...
4.
Bleich D, Biggs M, Gardin J, Lyles M, Siscovick D, Mukamal K
Am J Prev Cardiol . 2024 Sep; 19:100725. PMID: 39286650
Aims: To determine whether discrete lipid profiles (refer to as lipid phenotyping) can be used to stratify cardiovascular risk in individuals with type 2 diabetes. Methods And Results: Cardiovascular Health...
5.
Tang W, Lemaitre R, Jensen P, Wang M, Wang Z, Li X, et al.
Circ Heart Fail . 2024 Aug; 17(8):e011569. PMID: 39119698
Background: Growing evidence indicates that trimethylamine -oxide, a gut microbial metabolite of dietary choline and carnitine, promotes both cardiovascular disease and chronic kidney disease risk. It remains unclear how circulating...
6.
Fretts A, Jensen P, Sitlani C, Hoofnagle A, Lidgard B, Umans J, et al.
J Am Heart Assoc . 2024 Jun; 13(13):e032536. PMID: 38904223
Background: A growing body of research indicates that associations of ceramides and sphingomyelins with mortality depend on the chain length of the fatty acid acylated to the backbone sphingoid base....
7.
Wang M, Tang W, Li X, de Oliveira Otto M, Lee Y, Lemaitre R, et al.
J Am Soc Nephrol . 2024 Apr; 35(6):749-760. PMID: 38593157
No abstract available.
8.
Vu T, Pirzada A, Lewis C, Schreiner P, Liu K, Sternfeld B, et al.
J Endocr Soc . 2024 Jan; 8(2):bvad174. PMID: 38213908
Context: There are no reported data from prospective long-term studies on the relation of androgen levels in young women with development of metabolic syndrome (MetS) before menopause. Objective: We investigated...
9.
OKeefe J, Tintle N, Harris W, OKeefe E, Sala-Vila A, Attia J, et al.
Stroke . 2023 Dec; 55(1):50-58. PMID: 38134264
Background: The effect of marine omega-3 PUFAs on risk of stroke remains unclear. Methods: We investigated the associations between circulating and tissue omega-3 PUFA levels and incident stroke (total, ischemic,...
10.
Bene-Alhasan Y, Siscovick D, Ix J, Kizer J, Tracy R, Djousse L, et al.
Metabol Open . 2023 Dec; 20:100261. PMID: 38115866
Aim: Non-esterified fatty acids (NEFA) are potential targets for prevention of key cardiometabolic diseases of aging, but their population-level correlates remain uncertain. We sought to identify modifiable factors associated with...