Josephine C Ferreon
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Explore the profile of Josephine C Ferreon including associated specialties, affiliations and a list of published articles.
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40
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1763
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Recent Articles
11.
Lee J, Wang R, Xiong F, Krakowiak J, Liao Z, Nguyen P, et al.
Mol Cell
. 2021 Aug;
81(16):3368-3385.e9.
PMID: 34375583
The mechanistic understanding of nascent RNAs in transcriptional control remains limited. Here, by a high sensitivity method methylation-inscribed nascent transcripts sequencing (MINT-seq), we characterized the landscapes of N6-methyladenosine (m6A) on...
12.
Tsoi P, Quan M, Choi K, Dao K, Ferreon J, Ferreon A
Protein Sci
. 2021 May;
30(7):1408-1417.
PMID: 33982369
Membrane-less organelles and RNP granules are enriched in RNA and RNA-binding proteins containing disordered regions. Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1), a key regulating protein in RNA metabolism, localizes to cytoplasmic...
13.
Nguyen T, Kabotyanski E, Reineke L, Shao J, Xiong F, Lee J, et al.
Nucleic Acids Res
. 2019 Dec;
48(5):2621-2642.
PMID: 31863590
Transposable elements (TEs) comprise a large proportion of long non-coding RNAs (lncRNAs). Here, we employed CRISPR to delete a short interspersed nuclear element (SINE) in Malat1, a cancer-associated lncRNA, to...
14.
Mitra S, Kumar D, Hu L, Sankaran B, Moosa M, Rice A, et al.
J Virol
. 2019 Aug;
93(21).
PMID: 31375595
Influenza A virus (IAV) nonstructural protein 1 (NS1), a potent antagonist of the host immune response, is capable of interacting with RNA and a wide range of cellular proteins. NS1...
15.
Moosa M, Ferreon J, Ferreon A
Methods Mol Biol
. 2019 Feb;
1948:221-233.
PMID: 30771181
Misfolding and aggregation of α-synuclein are linked to many neurodegenerative disorders, including Parkinson's and Alzheimer's disease. Despite intense research efforts, detailed structural characterization of early conformational transitions that initiate and...
16.
Choi K, Tsoi P, Moosa M, Paulucci-Holthauzen A, Liao S, Ferreon J, et al.
Biochemistry
. 2018 Dec;
57(50):6822-6826.
PMID: 30520303
Ribonucleoprotein (RNP) condensations through liquid-liquid phase separation play vital roles in the dynamic formation-dissolution of stress granules (SGs). These condensations are, however, usually assumed to be linked to pathologic fibrillation....
17.
Moosa M, Tsoi P, Choi K, Ferreon A, Ferreon J
Int J Mol Sci
. 2018 Dec;
19(12).
PMID: 30518054
Sox2 is a pioneer transcription factor that initiates cell fate reprogramming through locus-specific differential regulation. Mechanistically, it was assumed that Sox2 achieves its regulatory diversity via heterodimerization with partner transcription...
18.
Ramani S, Stewart C, Laucirica D, Ajami N, Robertson B, Autran C, et al.
Nat Commun
. 2018 Nov;
9(1):5010.
PMID: 30479342
Neonatal rotavirus infections are predominantly asymptomatic. While an association with gastrointestinal symptoms has been described in some settings, factors influencing differences in clinical presentation are not well understood. Using multidisciplinary...
19.
Hu L, Sankaran B, Laucirica D, Patil K, Salmen W, Ferreon A, et al.
Nat Commun
. 2018 Jul;
9(1):2631.
PMID: 29980685
Rotaviruses (RVs) cause life-threatening diarrhea in infants and children worldwide. Recent biochemical and epidemiological studies underscore the importance of histo-blood group antigens (HBGA) as both cell attachment and susceptibility factors...
20.
Moosa M, Ferreon J, Ferreon A
Semin Cell Dev Biol
. 2018 May;
99:78-85.
PMID: 29753880
Intrinsically disordered proteins as computationally predicted account for ∼1/3 of eukaryotic proteomes, are involved in a plethora of biological functions, and have been linked to several human diseases as a...