Allan Chris M Ferreon
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Explore the profile of Allan Chris M Ferreon including associated specialties, affiliations and a list of published articles.
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38
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1203
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Recent Articles
1.
Lucas L, Tsoi P, Quan M, Choi K, Ferreon J, Ferreon A
bioRxiv
. 2025 Mar;
PMID: 40060635
Proteins phase-separate to form condensates that partition and concentrate biomolecules into membraneless compartments. These condensates can exhibit dichotomous behaviors in biology by supporting cellular physiology or instigating pathological protein aggregation...
2.
Ferreon J, Kongchan N, Tsoi P, Choi K, Kenrick S, Neilson J, et al.
ACS Omega
. 2024 Oct;
9(39):41003-41010.
PMID: 39371993
Many RNA-binding proteins, such as TDP-43 or CELF1, interact multivalently with nucleic acid repetitive elements. The molecular stoichiometry of protein to nucleic acid is often difficult to assess, particularly by...
3.
Tsoi P, Ferreon J, Ferreon A
Int J Mol Sci
. 2024 Jul;
25(13).
PMID: 38999934
Biomolecular condensates (BMCs) exhibit physiological and pathological relevance in biological systems. Both liquid and solid condensates play significant roles in the spatiotemporal regulation and organization of macromolecules and their biological...
4.
Ferreon J, Ta H, Yun H, Choi K, Quan M, Tsoi P, et al.
Biochemistry
. 2024 Apr;
63(9):1067-1074.
PMID: 38619104
NANOG protein levels correlate with stem cell pluripotency. NANOG concentrations fluctuate constantly with low NANOG levels leading to spontaneous cell differentiation. Previous literature implicated Pin1, a phosphorylation-dependent prolyl isomerase, as...
5.
Quan M, Ferreon J, Ferreon A
Nat Chem Biol
. 2024 Feb;
20(4):399-400.
PMID: 38326412
No abstract available.
6.
Tsoi P, Quan M, Ferreon J, Ferreon A
Int J Mol Sci
. 2023 Feb;
24(4).
PMID: 36834792
Cellular deposition of protein aggregates, one of the hallmarks of neurodegeneration, disrupts cellular functions and leads to neuronal death. Mutations, posttranslational modifications, and truncations are common molecular underpinnings in the...
7.
Quan M, Liao S, Ferreon J, Ferreon A
Methods Mol Biol
. 2022 Oct;
2563:135-148.
PMID: 36227471
Biomolecular condensates of ribonucleoproteins (RNPs) such as the transactivation response element (TAR) DNA-binding protein 43 (TDP-43) arise from liquid-liquid phase separation (LLPS) and play vital roles in various biological processes...
8.
Choi K, Quan M, Qi C, Lee J, Tsoi P, Zahabiyon M, et al.
Nat Cell Biol
. 2022 Apr;
24(5):737-747.
PMID: 35484250
Human NANOG expression resets stem cells to ground-state pluripotency. Here we identify the unique features of human NANOG that relate to its dose-sensitive function as a master transcription factor. NANOG...
9.
Sharma R, Choi K, Quan M, Sharma S, Sankaran B, Park H, et al.
Nat Commun
. 2021 Sep;
12(1):5579.
PMID: 34552088
Expression of a few master transcription factors can reprogram the epigenetic landscape and three-dimensional chromatin topology of differentiated cells and achieve pluripotency. During reprogramming, thousands of long-range chromatin contacts are...
10.
Tsoi P, Quan M, Choi K, Dao K, Ferreon J, Ferreon A
Protein Sci
. 2021 May;
30(7):1408-1417.
PMID: 33982369
Membrane-less organelles and RNP granules are enriched in RNA and RNA-binding proteins containing disordered regions. Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1), a key regulating protein in RNA metabolism, localizes to cytoplasmic...