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Joseph W Adelsberger

Explore the profile of Joseph W Adelsberger including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 1044
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Recent Articles
11.
Swaminathan S, Sui H, Adelsberger J, Chen Q, Sneller M, Migueles S, et al.
J AIDS Clin Res . 2015 May; 5(6). PMID: 26023356
Objectives: After DNA or RNA virus infection, cytosolic foreign DNA or RNA derived from the infecting viruses is recognized by intracellular pathogen recognition receptors (PRRs) and induces activation of the...
12.
Imamichi H, Natarajan V, Adelsberger J, Rehm C, Lempicki R, Das B, et al.
AIDS . 2014 Feb; 28(8):1091-9. PMID: 24492253
Objective: Determining the precise lifespan of human T-cell is challenging due to the inability of standard techniques to distinguish between dividing and dying cells. Here, we measured the lifespan of...
13.
Oguariri R, Dai L, Adelsberger J, Rupert A, Stevens R, Yang J, et al.
J Biol Chem . 2013 May; 288(24):17812-22. PMID: 23640893
IL-2 has been used in culture of primary T cells to maintain cell proliferation. We have previously reported that IL-27 inhibits HIV-1 replication in primary T cells in the presence...
14.
Dai L, Lidie K, Chen Q, Adelsberger J, Zheng X, Huang D, et al.
J Exp Med . 2013 Mar; 210(3):517-34. PMID: 23460728
The susceptibility of macrophages to HIV-1 infection is modulated during monocyte differentiation. IL-27 is an anti-HIV cytokine that also modulates monocyte activation. In this study, we present new evidence that...
15.
Voss J, Dobra A, Morse C, Kovacs J, Danner R, Munson P, et al.
Biol Res Nurs . 2013 Jan; 15(2):137-51. PMID: 23324479
Purpose: Human immunodeficiency virus (HIV)-related fatigue (HRF) is multicausal and potentially related to mitochondrial dysfunction caused by antiretroviral therapy with nucleoside reverse transcriptase inhibitors (NRTIs). Methodology: The authors compared gene...
16.
Imamichi H, Lempicki R, Adelsberger J, Hasley R, Rosenberg A, Roby G, et al.
Eur J Immunol . 2012 Jul; 42(10):2608-20. PMID: 22777759
HIV-induced immune activation leads to expansion of a subset of human CD8(+) T cells expressing HLA-DR antigens. Expansion of CD8(+) HLA-DR(+) T cells can be also observed in non-HIV settings...
17.
Voss J, Dobra A, Morse C, Kovacs J, Raju R, Danner R, et al.
Biol Res Nurs . 2011 Nov; 15(2):152-9. PMID: 22084402
Purpose: In limited samples of valuable biological tissues, univariate ranking methods of microarray analyses often fail to show significant differences among expression profiles. In order to allow for hypothesis generation,...
18.
Srinivasula S, Lempicki R, Adelsberger J, Huang C, Roark J, Lee P, et al.
Blood . 2011 May; 118(2):262-70. PMID: 21562041
We previously showed that HIV infection leads to expansion of a rapidly proliferating pool (s(1)) of CD4 and CD8 T lymphocytes. In the current study, we used in vivo labeling...
19.
Oguariri R, Adelsberger J, Baseler M, Imamichi T
Virus Res . 2010 Aug; 153(2):269-76. PMID: 20800626
Co-infection of human immunodeficiency virus (HIV) with malaria is one of the pandemic problems in Africa and parts of Asia. Here we investigated the impact of pyrimethamine (PYR) and two...
20.
Read S, DeGrezia M, Ciccone E, DerSimonian R, Higgins J, Adelsberger J, et al.
PLoS One . 2010 Aug; 5(8):e11937. PMID: 20689824
Background: The pathogenesis of immunodeficiency due to human immunodeficiency virus (HIV)-1 is incompletely understood, but immune activation is believed to play a central role. Immunomodulatory agents that decrease immune activation...