Richard A Lempicki
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Explore the profile of Richard A Lempicki including associated specialties, affiliations and a list of published articles.
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72
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40355
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Recent Articles
1.
Ma L, Chen Z, Huang D, Cisse O, Rothenburger J, Latinne A, et al.
mBio
. 2020 Mar;
11(2).
PMID: 32127451
, a major opportunistic pathogen in patients with a broad range of immunodeficiencies, contains abundant surface proteins encoded by a multicopy gene family, termed the major surface glycoprotein (Msg) gene...
2.
Cisse O, Ma L, Huang D, Khil P, Dekker J, Kutty G, et al.
mBio
. 2018 May;
9(3).
PMID: 29739910
species are opportunistic mammalian pathogens that cause severe pneumonia in immunocompromised individuals. These fungi are highly host specific and uncultivable Human infections present major challenges because of a limited therapeutic...
3.
Liang M, Raley C, Zheng X, Kutty G, Gogineni E, Sherman B, et al.
BioData Min
. 2016 Apr;
9:13.
PMID: 27051465
Background: Gene isoforms are commonly found in both prokaryotes and eukaryotes. Since each isoform may perform a specific function in response to changing environmental conditions, studying the dynamics of gene...
4.
Huang D, Raley C, Jiang M, Zheng X, Liang D, Rehman M, et al.
J Data Mining Genomics Proteomics
. 2016 Mar;
7(1).
PMID: 26949565
Development of HIV-1 drug resistance mutations (HDRMs) is one of the major reasons for the clinical failure of antiretroviral therapy. Treatment success rates can be improved by applying personalized anti-HIV...
5.
Ma L, Chen Z, Huang D, Kutty G, Ishihara M, Wang H, et al.
Nat Commun
. 2016 Feb;
7:10740.
PMID: 26899007
Pneumocystis jirovecii is a major cause of life-threatening pneumonia in immunosuppressed patients including transplant recipients and those with HIV/AIDS, yet surprisingly little is known about the biology of this fungal...
6.
Katsounas A, Frank A, Lempicki R, Polis M, Asmuth D, Kottilil S
J AIDS Clin Res
. 2015 Jun;
6(1).
PMID: 26052470
Objective: This study was aimed to correlate interferon (IFN) inducible gene (IFIG) expression and IFIG induction with viral-load (VL) and VL-kinetics of Human-Immunodeficiency-Virus (HIV) or Hepatitis-C-Virus (HCV) in HIV-positive patients...
7.
Bishop L, Lionakis M, Sassi M, Murphy P, Hu X, Huang D, et al.
Microbes Infect
. 2015 Jun;
17(9):638-50.
PMID: 26052064
We examined gene expression levels of multiple chemokines and chemokine receptors during Pneumocystis murina infection in wild-type and immunosuppressed mice, using microarrays and qPCR. In wild-type mice, expression of chemokines...
8.
Sidharthan S, Kim C, Murphy A, Zhang X, Yang J, Lempicki R, et al.
Front Immunol
. 2014 Jun;
5:248.
PMID: 24904592
This study examines the distinct gene expression profile of peripheral blood mononuclear cells from patients with chronic hepatitis C infection and mixed cryoglobulinemic (MC) vasculitis. Our DNA microarray analysis indicates...
9.
Katsounas A, Rasimas J, Schlaak J, Lempicki R, Rosenstein D, Kottilil S
J Med Virol
. 2014 May;
86(8):1323-31.
PMID: 24782267
Hepatitis C Virus (HCV) infection occurs frequently in patients with preexisting mental illness. Treatment for chronic hepatitis C using interferon formulations often increases risk for neuro-psychiatric symptoms. Pegylated-Interferon-α (PegIFN-α) remains...
10.
Ripamonti C, Bishop L, Yang J, Lempicki R, Kovacs J
Microbes Infect
. 2014 Apr;
16(6):522-7.
PMID: 24680862
To determine if myeloid differentiation factor 88 (MyD88), which is necessary for signaling by most TLRs and IL-1Rs, is necessary for control of Pneumocystis infection, MyD88-deficient and wild-type mice were...