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Joseph M Schober

Explore the profile of Joseph M Schober including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 446
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Recent Articles
1.
Scott N, Witt K, Schober J
Biotechniques . 2022 Nov; 73(6):273-279. PMID: 36398847
There are various approaches in which one can isolate microglia from murine brains, such as immunomagnetic, density gradient, FACS and differential adhesive methods. In this procedure a modified flask-tapping approach...
2.
Denn E, Schober J
Biotechniques . 2021 May; 70(5):278-284. PMID: 33969703
Cellular redox changes are common in apoptosis, immune function, signaling pathways and cancer. The authors aimed to develop a single-wavelength method using the superior fluorescence sensitivity of a flow cytometer...
3.
Gilda S, Schober J, McPherson T
Int J Pharm Compd . 2021 Jan; 25(1):48-51. PMID: 33503009
Water activity refers to the amount of water in a system that is available for microbial growth. Commercial water activity meters are precision instruments with the ability to determine water...
4.
Reimer M, Denby E, Zustiak S, Schober J
PLoS One . 2017 Dec; 12(12):e0189589. PMID: 29240845
IQGAP1 interacts with a number of binding partners through a calponin homology domain (CHD), a WW motif, IQ repeats, a Ras GAP-related domain (GRD), and a conserved C-terminal (CT) domain....
5.
Foroutannejad S, Rohner N, Reimer M, Kwon G, Schober J
Biochem Biophys Res Commun . 2014 Apr; 448(1):39-44. PMID: 24747073
IQGAP1 has emerged as a key component in the regulation of cytoskeleton dynamics during cell migration, maintenance of adherens junctions, microbial pathogenesis and intracellular trafficking. IQGAP1 is known to localize...
6.
Schober J, Kwon G, Jayne D, Cain J
Biochem Biophys Res Commun . 2011 Nov; 417(1):67-72. PMID: 22120625
The plus-ends of microtubules target the cell cortex to modulate actin protrusion dynamics and polarity, but little is known of the molecular mechanism that couples the interaction. EB1 protein associates...
7.
Lee H, Komarova Y, Nadezhdina E, Anjum R, Peloquin J, Schober J, et al.
Mol Biol Cell . 2010 Jun; 21(15):2661-73. PMID: 20519438
Cytoplasmic linker protein (CLIP)-170 is a microtubule (MT) plus-end-tracking protein that regulates MT dynamics and links MT plus ends to different intracellular structures. We have shown previously that intramolecular association...
8.
Schober J, Cain J, Komarova Y, Borisy G
Cancer Lett . 2009 May; 284(1):30-6. PMID: 19427113
Remodeling of actin and microtubule cytoskeletons is thought to be coupled; however, the interplay between these two systems is not fully understood. We show a microtubule end-binding protein, EB1, is...
9.
Komarova Y, de Groot C, Grigoriev I, Montenegro Gouveia S, Munteanu E, Schober J, et al.
J Cell Biol . 2009 Mar; 184(5):691-706. PMID: 19255245
End binding proteins (EBs) are highly conserved core components of microtubule plus-end tracking protein networks. Here we investigated the roles of the three mammalian EBs in controlling microtubule dynamics and...
10.
Schober J, Komarova Y, Chaga O, Akhmanova A, Borisy G
J Cell Sci . 2007 Mar; 120(Pt 7):1235-44. PMID: 17356063
Interaction between the microtubule system and actin cytoskeleton has emerged as a fundamental process required for spatial regulation of cell protrusion and retraction activities. In our current studies, analysis of...