Joseph El Khoury
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Explore the profile of Joseph El Khoury including associated specialties, affiliations and a list of published articles.
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9211
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Recent Articles
21.
Khoury B, El Khoury J, Fresan Orellana A, Daouk S, Khauli N, Ramadan Z, et al.
Cult Health Sex
. 2020 Feb;
23(1):131-142.
PMID: 32031503
The aim of this study was to evaluate the adequacy of the then proposed International Classification of Diseases version 11 (ICD-11) diagnostic guidelines for Gender Incongruence of Adolescence and Adulthood...
22.
Hickman S, Allison E, Coleman U, Kingery-Gallagher N, El Khoury J
Front Immunol
. 2019 Dec;
10:2780.
PMID: 31849963
CX3CR1 is a chemokine receptor expressed on microglia that binds Fractalkine (CX3CL1) and regulates microglial recruitment to sites of neuroinflammation. Full deletion of CX3CR1 in mouse models of Alzheimer's disease...
23.
Abels E, Maas S, Nieland L, Wei Z, Cheah P, Tai E, et al.
Cell Rep
. 2019 Sep;
28(12):3105-3119.e7.
PMID: 31533034
Gliomas are primary, diffusely infiltrating brain tumors. Microglia are innate immune cells in the CNS and make up a substantial portion of the tumor mass. Glioma cells shape their microenvironment,...
24.
Izzy S, Liu Q, Fang Z, Lule S, Wu L, Chung J, et al.
Front Cell Neurosci
. 2019 Aug;
13:307.
PMID: 31440141
The neuroinflammatory response to traumatic brain injury (TBI) is critical to both neurotoxicity and neuroprotection, and has been proposed as a potentially modifiable driver of secondary injury in animal and...
25.
Hickman S, El Khoury J
Methods Mol Biol
. 2019 Aug;
2034:305-323.
PMID: 31392695
Sensing changes in the brain milieu is a major microglial function that regulates the ability of these cells to perform other tasks including host defense and homeostasis. Microglia express a...
26.
Griciuc A, Patel S, Federico A, Choi S, Innes B, Oram M, et al.
Neuron
. 2019 Jul;
103(5):820-835.e7.
PMID: 31301936
The microglial receptors CD33 and TREM2 have been associated with risk for Alzheimer's disease (AD). Here, we investigated crosstalk between CD33 and TREM2. We showed that knockout of CD33 attenuated...
27.
Takizawa T, Qin T, de Morais A, Sugimoto K, Chung J, Morsett L, et al.
J Cereb Blood Flow Metab
. 2019 Jun;
40(5):1117-1131.
PMID: 31242047
Cortical spreading depolarization (CSD) induces pro-inflammatory gene expression in brain tissue. However, previous studies assessing the relationship between CSD and inflammation have used invasive methods that directly trigger inflammation. To...
28.
El Khoury J, Noufi P, Ahmad A, Akl E, El Hayek S
Drug Alcohol Depend
. 2019 Feb;
196:71-78.
PMID: 30716567
Background: Substance use has a tremendous impact on the burden of disease. This is particularly true in the Eastern Mediterranean region (EMR), where many countries serve as suppliers of drugs....
29.
El Khoury J, Adams D, Saliba C, Rayes J, Massin A, Fenoll C
Cureus
. 2018 Dec;
10(9):e3378.
PMID: 30510886
This paper describes the surgical findings and operative approach to treating a post-traumatic pseudolipoma. To the best of our knowledge this is the first case report that details the surgical...
30.
Hickman S, Izzy S, Sen P, Morsett L, El Khoury J
Nat Neurosci
. 2018 Sep;
21(10):1359-1369.
PMID: 30258234
The neuroimmune system is involved in development, normal functioning, aging, and injury of the central nervous system. Microglia, first described a century ago, are the main neuroimmune cells and have...