Joseph D Mancias
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Explore the profile of Joseph D Mancias including associated specialties, affiliations and a list of published articles.
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72
Citations
8867
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Recent Articles
11.
Fisher A, Wang C, Xu Y, Phillips S, Paulo J, Malachowska B, et al.
iScience
. 2023 Dec;
26(12):108555.
PMID: 38125029
Hepcidin is the master hormone governing systemic iron homeostasis. Iron regulates hepcidin by activating bone morphogenetic protein (BMP)6 expression in liver endothelial cells (LECs), but the mechanisms are incompletely understood....
12.
Ali L, Lenehan P, Cardot-Ruffino V, Dias Costa A, Katz M, Bauer T, et al.
Clin Cancer Res
. 2023 Sep;
30(3):542-553.
PMID: 37733830
Purpose: Pancreatic ductal adenocarcinoma (PDAC) trials have evaluated CTLA-4 and/or PD-(L)1 blockade in patients with advanced disease in which bulky tumor burden and limited time to develop antitumor T cells...
13.
Smart A, Liu K, Domogauer J, Rodriguez-Russo C, Jones B, Dickstein D, et al.
Int J Radiat Oncol Biol Phys
. 2023 May;
117(2):301-311.
PMID: 37230432
Access to gender-affirming surgery is increasing for many transgender and nonbinary people in the United States, and radiation oncologists must be equipped to care for patients who have undergone such...
14.
Jitendra Parikh P, Lee P, Low D, Kim J, Mittauer K, Bassetti M, et al.
Int J Radiat Oncol Biol Phys
. 2023 May;
117(4):799-808.
PMID: 37210048
Purpose: Magnetic resonance (MR) image guidance may facilitate safe ultrahypofractionated radiation dose escalation for inoperable pancreatic ductal adenocarcinoma. We conducted a prospective study evaluating the safety of 5-fraction Stereotactic MR-guided...
15.
Mukhopadhyay S, Encarnacion-Rosado J, Lin E, Sohn A, Zhang H, Mancias J, et al.
Sci Adv
. 2023 Apr;
9(16):eadf9284.
PMID: 37075122
Pancreatic ductal adenocarcinoma (PDAC) cells maintain a high level of autophagy, allowing them to thrive in an austere microenvironment. However, the processes through which autophagy promotes PDAC growth and survival...
16.
Chen B, Das N, Talukder I, Singhal R, Castillo C, Andren A, et al.
J Biol Chem
. 2023 Apr;
299(5):104691.
PMID: 37037306
Mitophagy is a cargo-specific autophagic process that recycles damaged mitochondria to promote mitochondrial turnover. PTEN-induced putative kinase 1 (PINK1) mediates the canonical mitophagic pathway. However, the role of PINK1 in...
17.
Han Z, Sudhyadhom A, Hsu S, Hu Y, Mak R, Huynh M, et al.
J Appl Clin Med Phys
. 2023 Mar;
24(7):e13965.
PMID: 36924220
Purpose: The role of biliary stents in image-guided localization for pancreatic cancer has been inconclusive. To date, stent accuracy has been largely evaluated against implanted fiducials on cone beam computed...
18.
Smyczynska U, Stanczak M, Kuljanin M, Wlodarczyk A, Stoczynska-Fidelus E, Taha J, et al.
Genes (Basel)
. 2022 Dec;
13(12).
PMID: 36553637
Alström syndrome (ALMS) and Bardet-Biedl syndrome (BBS) are rare genetic diseases with a number of common clinical features ranging from early-childhood obesity and retinal degeneration. ALMS and BBS belong to...
19.
Williams H, Dias Costa A, Zhang J, Raghavan S, Winter P, Kapner K, et al.
Cancer Res
. 2022 Dec;
83(3):441-455.
PMID: 36459568
Significance: A high-throughput pipeline using multiplex immunofluorescence in pancreatic cancer reveals striking expression subtype intratumoral heterogeneity with implications for therapy selection and identifies co-expressor cells that may serve as intermediates...
20.
Fan M, Lu W, Che J, Kwiatkowski N, Gao Y, Seo H, et al.
Elife
. 2022 Oct;
11.
PMID: 36300789
The transcription factor TEAD, together with its coactivator YAP/TAZ, is a key transcriptional modulator of the Hippo pathway. Activation of TEAD transcription by YAP has been implicated in a number...