Joseph C LaManna
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Explore the profile of Joseph C LaManna including associated specialties, affiliations and a list of published articles.
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99
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2274
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Recent Articles
1.
LaManna J
Adv Exp Med Biol
. 2024 Oct;
1463:27-31.
PMID: 39400795
From its inception, the International Society of Oxygen Transport to Tissue (ISOTT) included several core members who were intrigued by the possibility of using light to probe the metabolic state...
2.
Bindra S, LaManna J, Xu K
Adv Exp Med Biol
. 2021 May;
1269:329-333.
PMID: 33966238
The mammalian brain modulates its microvascular network to accommodate tissue energy demand in a process referred to as angioplasticity. There is an aging effect on cognitive function and adaptive responses...
3.
Darlington T, LaManna J, Xu K
Adv Exp Med Biol
. 2021 May;
1269:317-322.
PMID: 33966236
We have previously reported that in a rat model of chronic hypoxia, HIF-1α and its target genes have significantly accumulated by 3 days of exposure, whereas no significant increase in...
4.
Ma L, Garcia-Medina J, Ortet G, LaManna J, Xu K
Adv Exp Med Biol
. 2021 May;
1269:271-276.
PMID: 33966229
Hypoxia-inducible factors (HIFs) are transcriptional regulators that mediate in mice for HIF-1 and HIF-2. The objective of this study was to investigate the effect of neuronal deletion of HIF-1 and...
5.
Sethuraman A, Rao P, Pranay A, Xu K, LaManna J, Puchowicz M
Adv Exp Med Biol
. 2021 May;
1269:3-7.
PMID: 33966187
Hypoxia inducible factor alpha (HIF1α) is associated with neuroprotection conferred by diet-induced ketosis, but the underlying mechanism remains unclear. In this study, we use a ketogenic diet in rodents to...
6.
Damato E, Flak T, Mayes R, Strohl K, Ziganti A, Abdollahifar A, et al.
J Physiol
. 2020 Nov;
598(18):3941-3956.
PMID: 33174711
Key Points: Extreme aviation is accompanied by ever-present risks of hypobaric hypoxia and decompression sickness. Neuroprotection against those hazards is conferred through fractional inspired oxygen ( ) concentrations of 60-100%...
7.
Thews O, LaManna J, Harrison D
Adv Exp Med Biol
. 2019 Oct;
1072:C1.
PMID: 31586355
The chapters "Changes in Cytochrome-C-Oxidase Account for Changes in Attenuation of Near-Infrared Light in the Healthy Infant Brain" and "Fibreless Multiwavelength NIRS System for Imaging Localised Changes in Cerebral Oxidised...
8.
Zhang Y, Xu K, Liu Y, Erokwu B, Zhao P, Flask C, et al.
PLoS One
. 2019 Jun;
14(6):e0218415.
PMID: 31220136
Aquaporin-4 (AQP4) plays an important role in regulating water exchange across the blood-brain barrier (BBB) and brain-cerebrospinal fluid interface. Studies on AQP-4 knockout mice (AQP4-KO) have reported considerable protection from...
9.
Farr G, Hall C, Farr S, Wade R, Detzel J, Adams A, et al.
Neuroscience
. 2019 Feb;
404:484-498.
PMID: 30738082
Cerebral edema in ischemic stroke can lead to increased intracranial pressure, reduced cerebral blood flow and neuronal death. Unfortunately, current therapies for cerebral edema are either ineffective or highly invasive....
10.
Xu K, Puchowicz M, LaManna J
Adv Exp Med Biol
. 2018 Sep;
1072:77-82.
PMID: 30178327
Transient global brain ischemia, induced by cardiac arrest and resuscitation, results in reperfusion injury leading to delayed selective neuronal cell loss and post-resuscitation mortality. This study determined the effects of...