Joseph C LaManna
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Explore the profile of Joseph C LaManna including associated specialties, affiliations and a list of published articles.
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99
Citations
2274
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Recent Articles
11.
Zhang Y, Xu K, Kerwin T, LaManna J, Puchowicz M
Adv Exp Med Biol
. 2018 Sep;
1072:21-25.
PMID: 30178318
Neuroprotection by ketosis is thought to be associated with improved mitochondrial function, decreased reactive oxygen species (ROS) and apoptotic and inflammatory mediators, and increased protective pathways. Oxidative injury to cells...
12.
LaManna J
Adv Exp Med Biol
. 2018 Sep;
1072:3-6.
PMID: 30178315
In order to maintain proper function, mammalian brain requires a significant fraction of the energy provided through whole body oxygen consumption and oxidative phosphorylation. This has been fairly well known...
13.
Xu K, Bhupanapadu Sunkesula S, Huang P, Tsipis C, Radford T, Babcock G, et al.
Adv Exp Med Biol
. 2018 Apr;
765:E3.
PMID: 29651782
No abstract available.
14.
Xu K, Ye L, Sharma K, Jin Y, Harrison M, Caldwell T, et al.
Adv Exp Med Biol
. 2017 Jul;
977:205-213.
PMID: 28685447
Over the past decade we have consistently shown that ketosis is neuroprotective against ischemic insults in rats. We reported that diet-induced ketotic rats had a significant reduction in infarct volume...
15.
He C, Tsipis C, LaManna J, Xu K
Adv Exp Med Biol
. 2017 Jul;
977:175-181.
PMID: 28685443
Enrichment provides an environment that fosters increased physical activity and sensory stimulation as compared to standard housing. Promoting and sustaining stimulation increases neuronal activity and, consequently, brain oxygen demand. The...
16.
Xu K, Boas D, Sakadzic S, LaManna J
Adv Exp Med Biol
. 2017 Jul;
977:149-153.
PMID: 28685439
Key to the understanding of the principles of physiological and structural acclimatization to changes in the balance between energy supply (represented by substrate and oxygen delivery, and mitochondrial oxidative phosphorylation)...
17.
Xu K, Sun X, Benderro G, Tsipis C, LaManna J
Physiol Rep
. 2017 Mar;
5(4).
PMID: 28242826
The aim of this study was to determine the effect of cyclooxygenase-2 (COX-2) gene deletion on the adaptive responses during prolonged moderate hypobaric hypoxia. Wild-type (WT) and COX-2 knockout (KO)...
18.
Protective Effect of Dl-3-n-Butylphthalide on Recovery from Cardiac Arrest and Resuscitation in Rats
Zhang L, Puchowicz M, LaManna J, Xu K
Adv Exp Med Biol
. 2016 Aug;
923:31-36.
PMID: 27526121
In this study we investigated the effect of Dl-3-n-butylphthalide (NBP), a clinically used drug for stroke patients in China, on the recovery following cardiac arrest and resuscitation in rats. Male...
19.
Xu K, Puchowicz M, LaManna J
Adv Exp Med Biol
. 2016 Jan;
876:265-270.
PMID: 26782221
In this study we investigated the effect of aging on brain blood flow following transient global ischemia. Male Fisher rats (6 and 24 months old) underwent cardiac arrest (15 min)...
20.
Benderro G, LaManna J
Brain Res
. 2014 May;
1569:41-7.
PMID: 24796880
Dynamic microvascular remodeling maintains an optimal continuous supply of oxygen and nutrients to the brain to account for prolonged environmental variations. The objective of this study was to determine the...