Jose L Carrascosa
Overview
Explore the profile of Jose L Carrascosa including associated specialties, affiliations and a list of published articles.
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119
Citations
2946
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Recent Articles
1.
Dauden M, Perez-Ruiz M, Carrascosa J, Cuervo A
Subcell Biochem
. 2024 Dec;
105:469-502.
PMID: 39738955
Viruses shield their genetic information by enclosing the viral nucleic acid inside a protein shell (capsid), in a process known as genome packaging. Viruses follow essentially two main strategies to...
2.
Carrascosa J
Adv Exp Med Biol
. 2024 Mar;
3234:191-205.
PMID: 38507208
Recent advancements in cryo-electron microscopy (cryo-TEM) have enabled the determination of structures of macromolecular complexes at near-atomic resolution, establishing it as a pivotal tool in Structural Biology. This high resolution...
3.
Cuervo A, Losana P, Carrascosa J
Methods Mol Biol
. 2023 Dec;
2734:13-25.
PMID: 38066360
Transmission electron microscopy (TEM) is an ideal method to observe and determine the structure of bacteriophages. From early studies by negative staining to the present atomic structure models derived from...
4.
Perez-Berna A, Benseny-Cases N, Rodriguez M, Valcarcel R, Carrascosa J, Gastaminza P, et al.
Acta Crystallogr D Struct Biol
. 2021 Nov;
77(Pt 11):1365-1377.
PMID: 34726165
Hepatitis C virus (HCV) is an enveloped RNA virus. One of the hallmarks of HCV infection is a rearrangement of the host cell membranes, known as the `membranous web'. Full-field...
5.
Perez-Ruiz M, Pulido-Cid M, Luque-Ortega J, Valpuesta J, Cuervo A, Carrascosa J
Proc Natl Acad Sci U S A
. 2021 Aug;
118(34).
PMID: 34417311
In most bacteriophages, genome transport across bacterial envelopes is carried out by the tail machinery. In viruses of the family, in which the tail is not long enough to traverse...
6.
Fabrega-Ferrer M, Cuervo A, Fernandez F, Machon C, Perez-Luque R, Pous J, et al.
Acta Crystallogr D Struct Biol
. 2021 Jan;
77(Pt 1):11-18.
PMID: 33404521
Medium-resolution cryo-electron microscopy maps, in particular when they include a significant number of α-helices, may allow the building of partial models that are useful for molecular-replacement searches in large crystallographic...
7.
Conesa J, Sevilla E, Terron M, Gonzalez L, Gray J, Perez-Berna A, et al.
mSphere
. 2020 Oct;
5(5).
PMID: 33055261
is an apicomplexan parasite of significance that causes the disease known as babesiosis in domestic and wild animals and in humans worldwide. infects vertebrate hosts and reproduces asexually by a...
8.
Arribillaga L, Echeverria I, Belsue V, Gomez T, Lozano T, Casares N, et al.
J Immunother Cancer
. 2020 Jun;
8(1).
PMID: 32581060
Background: In vivo targeting of human papillomavirus (HPV) derived antigens to dendritic cells might constitute an efficient immunotherapeutic strategy against cervical cancer. In previous works, we have shown that the...
9.
Raman S, Mejias-Perez E, Gomez C, Garcia-Arriaza J, Perdiguero B, Vijayan A, et al.
Front Immunol
. 2019 Dec;
10:2793.
PMID: 31867001
There is an urgent need for the development of potent vaccination regimens that are able to induce specific T and B cell responses against human immunodeficiency virus type 1 (HIV-1)....
10.
Conesa J, Carrasco A, Rodriguez-Fanjul V, Yang Y, Carrascosa J, Cloetens P, et al.
Angew Chem Int Ed Engl
. 2019 Nov;
59(3):1270-1278.
PMID: 31697000
The iridium half-sandwich complex [Ir(η :κ -C Me CH py)(2-phenylpyridine)]PF is highly cytotoxic: 15-250× more potent than clinically used cisplatin in several cancer cell lines. We have developed a correlative...