Jose Francisco Lopez-Acosta
Overview
Explore the profile of Jose Francisco Lopez-Acosta including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
88
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0
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Recent Articles
1.
Sarno F, Tenorio J, Perea S, Medina L, Pazo-Cid R, Juez I, et al.
Clin Cancer Res
. 2024 Nov;
31(2):278-287.
PMID: 39540844
Purpose: Pancreatic ductal adenocarcinoma (PDAC) has limited treatment options. We compared the efficacy of comprehensive precision medicine against that of the conventional treatment in PDAC. Patients And Methods: We report...
2.
Zagorac I, Fernandez-Gaitero S, Penning R, Post H, Bueno M, Mouron S, et al.
Nat Commun
. 2018 Aug;
9(1):3501.
PMID: 30158526
Triple-negative breast cancer (TNBC) lacks prognostic and predictive markers. Here, we use high-throughput phosphoproteomics to build a functional TNBC taxonomy. A cluster of 159 phosphosites is upregulated in relapsed cases...
3.
Diaz-Ganete A, Baena-Nieto G, Lomas-Romero I, Lopez-Acosta J, Cozar-Castellano I, Medina F, et al.
Int J Endocrinol
. 2015 Aug;
2015:235727.
PMID: 26257781
Ghrelin is a peptidic hormone, which stimulates cell proliferation and inhibits apoptosis in several tissues, including pancreas. In preclinical stage of type 1 diabetes, proinflammatory cytokines generate a destructive environment...
4.
Jimenez-Palomares M, Lopez-Acosta J, Villa-Perez P, Moreno-Amador J, Munoz-Barrera J, Fernandez-Luis S, et al.
Am J Physiol Endocrinol Metab
. 2015 Jan;
308(6):E450-9.
PMID: 25564474
Activation of pancreatic β-cell proliferation has been proposed as an approach to replace reduced functional β-cell mass in diabetes. Quiescent fibroblasts exit from G0 (quiescence) to G1 through pRb phosphorylation...
5.
Lopez-Acosta J, Moreno-Amador J, Jimenez-Palomares M, Diaz-Marrero A, Cueto M, Perdomo G, et al.
PLoS One
. 2013 Jan;
8(1):e52862.
PMID: 23300997
There is an urgency to find new treatments for the devastating epidemic of diabetes. Pancreatic β-cells viability and function are impaired in the two most common forms of diabetes, type...
6.
Jimenez-Palomares M, Ramos-Rodriguez J, Lopez-Acosta J, Pacheco-Herrero M, Lechuga-Sancho A, Perdomo G, et al.
Am J Physiol Endocrinol Metab
. 2012 Mar;
302(11):E1373-80.
PMID: 22414803
Type 2 diabetes (T2D) mellitus and Alzheimer's disease (AD) are two prevalent diseases with comparable pathophysiological features and genetic predisposition. Patients with AD are more susceptible to develop T2D. However,...