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Jos A Cox

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Articles 14
Citations 347
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Recent Articles
1.
Cox J
Methods Mol Biol . 2013 Jan; 963:15-35. PMID: 23296602
Intracellular Ca(2+)-binding proteins (CaBPs) are sensors of the calcium signal and several of them even shape the signal. Most of them are equipped with at least two EF-hand motifs designed...
2.
Radu L, Durussel I, Assairi L, Blouquit Y, Miron S, Cox J, et al.
Biochemistry . 2010 Apr; 49(20):4383-94. PMID: 20408559
Centrins are calcium binding proteins that belong to the EF-hand (or calmodulin) superfamily, which are highly conserved among eukaryotes. Herein, we report the molecular features and binding properties of the...
3.
Ojha M, Cattaneo A, Hugh S, Pawlowski J, Cox J
Gene . 2010 Mar; 457(1-2):25-34. PMID: 20214955
Allomyces arbuscula, a primitive chytridiomycete fungus, has two Ca(2+)-dependent cysteine proteases, the CDP I and CDP II. We have cloned and analyzed the nucleotide sequence of CDP II gene and...
4.
Tirone F, Radu L, Craescu C, Cox J
Biochemistry . 2009 Dec; 49(4):761-71. PMID: 20028137
NADPH oxidases (NOX) are important superoxide producing enzymes that regulate a variety of physiological and pathological processes such as bacteria killing, angiogenesis, sperm-oocyte fusion, and oxygen sensing. NOX5 is a...
5.
Tirone F, Cox J
FEBS Lett . 2007 Mar; 581(6):1202-8. PMID: 17346712
Superoxide generation by NADPH oxidase 5 (NOX5) is regulated by Ca(2+) through intramolecular activation of the C-terminal catalytic domain by the EF-hand-containing N-terminal regulatory domain. The C terminus contains a...
6.
Sturchler E, Cox J, Durussel I, Weibel M, Heizmann C
J Biol Chem . 2006 Oct; 281(50):38905-17. PMID: 17030513
S100A16 protein is a new and unique member of the EF-hand Ca(2+)-binding proteins. S100 proteins are cell- and tissue-specific and are involved in many intra- and extracellular processes through interacting...
7.
Rabah G, Popescu R, Cox J, Engelborghs Y, Craescu C
FEBS J . 2005 Apr; 272(8):2022-36. PMID: 15819893
The solution structure of Nereis diversicolor sarcoplasmic calcium-binding protein (NSCP) in the calcium-bound form was determined by NMR spectroscopy, distance geometry and simulated annealing. Based on 1859 NOE restraints and...
8.
Cox J, Tirone F, Durussel I, Firanescu C, Blouquit Y, Duchambon P, et al.
Biochemistry . 2005 Jan; 44(3):840-50. PMID: 15654740
There are four isoforms of centrin in mammals, with variable sequence, tissue expression, and functional properties. We have recently characterized a number of structural, ion, and target binding properties of...
9.
Banfi B, Tirone F, Durussel I, Knisz J, Moskwa P, Molnar G, et al.
J Biol Chem . 2004 Feb; 279(18):18583-91. PMID: 14982937
NADPH oxidase 5 (NOX5) is a homologue of the gp91(phox) subunit of the phagocyte NADPH oxidase. NOX5 is expressed in lymphoid organs and testis and distinguished from the other NADPH...
10.
Gombos Z, Durussel I, Ikura M, Rose D, Cox J, Chakrabartty A
Biochemistry . 2003 May; 42(18):5531-9. PMID: 12731896
Calexcitin (CE) is a calcium sensor protein that has been implicated in associative learning through the Ca(2+)-dependent inhibition of K(+) channels and activation of ryanodine receptors. CE(B), the major CE...