Simona Miron
Overview
Explore the profile of Simona Miron including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
700
Followers
0
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Recent Articles
1.
Miron S, Legrand P, Dupaigne P, van Rossum-Fikkert S, Ristic D, Majeed A, et al.
Nucleic Acids Res
. 2024 Jun;
52(12):7337-7353.
PMID: 38828772
In vertebrates, the BRCA2 protein is essential for meiotic and somatic homologous recombination due to its interaction with the RAD51 and DMC1 recombinases through FxxA and FxPP motifs (here named...
2.
Gelot C, Kovacs M, Miron S, Mylne E, Haan A, Boeffard-Dosierre L, et al.
Nature
. 2024 Jan;
626(7999):E13.
PMID: 38273133
No abstract available.
3.
Alvaro-Aranda L, Petitalot A, Djeghmoum Y, Panigada D, Singh J, Ehlen A, et al.
Nucleic Acids Res
. 2023 Dec;
52(12):6964-6976.
PMID: 38142462
BRCA2 tumor suppressor protein ensures genome integrity by mediating DNA repair via homologous recombination (HR). This function is executed in part by its canonical DNA binding domain located at the...
4.
Ghouil R, Miron S, Sato K, Ristic D, van Rossum-Fikkert S, Legrand P, et al.
Sci Adv
. 2023 Oct;
9(43):eadi7352.
PMID: 37889963
In meiotic homologous recombination (HR), BRCA2 facilitates loading of the recombinases RAD51 and DMC1 at the sites of double-strand breaks (DSBs). The HSF2BP-BRME1 complex interacts with BRCA2. Its absence causes...
5.
Gelot C, Kovacs M, Miron S, Mylne E, Haan A, Boeffard-Dosierre L, et al.
Nature
. 2023 Sep;
621(7978):415-422.
PMID: 37674080
DNA double-strand breaks (DSBs) are deleterious lesions that challenge genome integrity. To mitigate this threat, human cells rely on the activity of multiple DNA repair machineries that are tightly regulated...
6.
Marcelot A, Rodriguez-Tirado F, Cuniasse P, Joiner M, Miron S, Soshnev A, et al.
Cells
. 2023 Mar;
12(6).
PMID: 36980188
Barrier-to-autointegration factor (BAF) is an essential component of the nuclear lamina. Encoded by , this DNA binding protein contributes to the regulation of gene expression, cell cycle progression, and nuclear...
7.
Ghouil R, Miron S, Koornneef L, Veerman J, Paul M, Le Du M, et al.
Nat Commun
. 2021 Jul;
12(1):4605.
PMID: 34326328
BRCA2 and its interactors are required for meiotic homologous recombination (HR) and fertility. Loss of HSF2BP, a BRCA2 interactor, disrupts HR during spermatogenesis. We test the model postulating that HSF2BP...
8.
Roisne-Hamelin F, Pobiega S, Jezequel K, Miron S, Depagne J, Veaute X, et al.
Nat Commun
. 2021 May;
12(1):2763.
PMID: 33980827
Specific proteins present at telomeres ensure chromosome end stability, in large part through unknown mechanisms. In this work, we address how the Saccharomyces cerevisiae ORC-related Rif2 protein protects telomere. We...
9.
Marcelot A, Petitalot A, Ropars V, Le Du M, Samson C, Dubois S, et al.
Nucleic Acids Res
. 2021 Mar;
49(7):3841-3855.
PMID: 33744941
Barrier-to-autointegration factor (BAF), encoded by the BANF1 gene, is an abundant and ubiquitously expressed metazoan protein that has multiple functions during the cell cycle. Through its ability to cross-bridge two...
10.
Ehlen A, Martin C, Miron S, Julien M, Theillet F, Ropars V, et al.
Nat Commun
. 2020 Apr;
11(1):1819.
PMID: 32286328
The BRCA2 tumor suppressor protein is involved in the maintenance of genome integrity through its role in homologous recombination. In mitosis, BRCA2 is phosphorylated by Polo-like kinase 1 (PLK1). Here...