Jorge Morales-Valencia
Overview
Explore the profile of Jorge Morales-Valencia including associated specialties, affiliations and a list of published articles.
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Snapshot
Snapshot
Articles
5
Citations
33
Followers
0
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Recent Articles
1.
Morales-Valencia J, Petit C, Calderon A, Saini S, David G
Mol Cancer Res
. 2023 Jun;
21(9):947-957.
PMID: 37314748
Implications: Identifying SIN3B as a modulator of DNA damage repair choice provides novel potential therapeutic avenues to sensitize cancer cells to cytotoxic therapies.
2.
Morales-Valencia J, Lau L, Marti-Nin T, Ozerdem U, David G
Oncogene
. 2022 Aug;
41(38):4361-4370.
PMID: 35953598
The acquisition of novel detrimental cellular properties following exposure to cytotoxic drugs leads to aggressive and metastatic tumors that often translates into an incurable disease. While the bulk of the...
3.
Morales-Valencia J, David G
Curr Opin Genet Dev
. 2022 May;
74:101914.
PMID: 35500379
Cancer cell dormancy has emerged as an important nongenetic driver of drug resistance. Dormant cells are characterized by a reversible cell cycle exit. They represent a reservoir for eventual cancer...
4.
Morales-Valencia J, David G
Front Oncol
. 2021 Oct;
11:747822.
PMID: 34621683
Senescent cells are found to accumulate in aged individuals, as well as in cancer patients that receive chemotherapeutic treatment. Although originally believed to halt cancer progression due to their characteristic...
5.
Vidal S, Polyzos A, Chatterjee K, Ee L, Swanzey E, Morales-Valencia J, et al.
Stem Cell Reports
. 2020 Sep;
15(6):1233-1245.
PMID: 32976761
Methylation of histone 3 at lysine 9 (H3K9) constitutes a roadblock for cellular reprogramming. Interference with methyltransferases or activation of demethylases by the cofactor ascorbic acid (AA) facilitates the derivation...