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Jorge Lloberas

Explore the profile of Jorge Lloberas including associated specialties, affiliations and a list of published articles. Areas
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Articles 44
Citations 1449
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Recent Articles
11.
Pereira-Lopes S, Celhar T, Sans-Fons G, Serra M, Fairhurst A, Lloberas J, et al.
J Immunol . 2013 Nov; 191(12):6128-35. PMID: 24218451
The three-prime repair exonuclease 1 (TREX1) is the most abundant exonuclease in mammalian cells. Mutations in Trex1 gene are being linked to the development of Aicardi-Goutières syndrome, an inflammatory disease...
12.
Sans-Fons M, Yeramian A, Pereira-Lopes S, Santamaria-Babi L, Modolell M, Lloberas J, et al.
J Infect Dis . 2013 Mar; 207(11):1684-93. PMID: 23460752
Host genetic factors play a crucial role in immune response. To determine whether the differences between C57Bl/6 and BALB-C mice are due only to the production of cytokines by T-helper...
13.
Serrat N, Pereira-Lopes S, Comalada M, Lloberas J, Celada A
Eur J Immunol . 2012 Aug; 42(11):3028-37. PMID: 22865229
The amount of arginine available at inflammatory loci is a limiting factor for the growth of several cells of the immune system. IL-4-induced activation of macrophages produced arginase-1, which converts...
14.
Comalada M, Lloberas J, Celada A
Eur J Immunol . 2012 Aug; 42(8):1938-48. PMID: 22865045
Macrophages play a central role in the immune response. These cells either proliferate in response to, for example, growth factors or become activated in response to, for example, LPS and...
15.
Comalada M, Yeramian A, Modolell M, Lloberas J, Celada A
Methods Mol Biol . 2012 Jan; 844:223-35. PMID: 22262446
In order to perform their functions, macrophages must be activated either by Th1-type cytokines, such as interferon-gamma which is called classical activation or M1, or by Th2-type cytokines, such as...
16.
Serra M, Forcales S, Pereira-Lopes S, Lloberas J, Celada A
J Immunol . 2011 Jan; 186(4):2299-308. PMID: 21239708
3' Repair exonuclease (Trex1) is the most abundant mammalian 3' → 5' DNA exonuclease with specificity for ssDNA. Trex1 deficiency has been linked to the development of autoimmune disease in...
17.
Valledor A, Comalada M, Santamaria-Babi L, Lloberas J, Celada A
Adv Immunol . 2010 Nov; 108:1-20. PMID: 21056727
Macrophages play key roles in inflammation. During the onset of the inflammatory process, these phagocytic cells become activated and have destructive effects. Macrophage activation, which involves the induction of more...
18.
Serrat N, Serra-Sarasa M, Barrachina M, Lloberas J, Celada A
Mol Immunol . 2009 Nov; 47(4):825-32. PMID: 19897249
The closest region of the promoter of MHC II genes and particularly three conserved boxes (X, Y and S) are fundamental for the transcriptional regulation. A second set of conserved...
19.
Sebastian C, Herrero C, Serra M, Lloberas J, Blasco M, Celada A
J Immunol . 2009 Jul; 183(4):2356-64. PMID: 19605693
Macrophages are an essential component of both innate and adaptive immunity, and altered function of these cells with aging may play a key role in immunosenescence. To determine the effect...
20.
Casals-Casas C, Alvarez E, Serra M, de la Torre C, Farrera C, Sanchez-Tillo E, et al.
Eur J Immunol . 2009 Jul; 39(7):1902-13. PMID: 19585511
MAPK phosphatase-1 (MKP-1) is a protein phosphatase that plays a crucial role in innate immunity. This phosphatase inactivates ERK1/2, which are involved in two opposite functional activities of the macrophage,...