Jorge D Miranda
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Explore the profile of Jorge D Miranda including associated specialties, affiliations and a list of published articles.
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29
Citations
398
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Recent Articles
1.
Pagan-Rivera L, Ocasio-Rivera S, Godoy-Vitorino F, Miranda J
Front Microbiol
. 2025 Jan;
15():1490855.
PMID: 39744391
Spinal cord injury (SCI) is a devastating pathological state causing motor, sensory, and autonomic dysfunction. To date, SCI remains without viable treatment for its patients. After the injury, molecular events...
2.
Colon-Mercado J, Torrado-Tapias A, Salgado I, Santiago J, Rivera S, Bracho-Rincon D, et al.
Neural Regen Res
. 2024 Sep;
20(11):3317-3329.
PMID: 39314150
JOURNAL/nrgr/04.03/01300535-202511000-00033/figure1/v/2024-12-20T164640Z/r/image-tiff In addition to the loss of motor function, ~ 60% of patients develop pain after spinal cord injury. The cellular-molecular mechanisms are not well understood, but the data suggests...
3.
Garcia-Sanchez L, Colon-Mercado J, Torrado-Tapias A, Padin-Diaz K, Miranda J, Santiago-Santana J
P R Health Sci J
. 2023 Mar;
42(1):23-28.
PMID: 36941095
Objective: We aimed to investigate estradiol (E2) as a therapeutic drug for spinal cord injury (SCI) and elucidate the disagreement in the field about the use of this hormone after...
4.
Martinez M, Martinez N, Miranda J, Maldonado H, Ortiz W
Biomolecules
. 2019 Oct;
9(10).
PMID: 31635212
Caveolae-associated protein caveolin-1 (Cav-1) plays key roles in cellular processes such as mechanosensing, receptor coupling to signaling pathways, cell growth, apoptosis, and cancer. In 1321N1 astrocytoma cells Cav-1 interacts with...
5.
Colon J, Gonzalez P, Cajigas A, Maldonado W, Torrado A, Santiago J, et al.
Exp Neurol
. 2017 Oct;
299(Pt A):109-121.
PMID: 29037533
No treatment is available for patients with spinal cord injury (SCI). Patients often arrive to the hospital hours after SCI suggesting the need of a therapy that can be used...
6.
Colon J, Miranda J
Neural Regen Res
. 2016 Sep;
11(8):1208-11.
PMID: 27651756
Spinal cord injury (SCI) is a condition without a cure, affecting sensory and/or motor functions. The physical trauma to the spinal cord initiates a cascade of molecular and cellular events...
7.
Cruz N, Miranda J, Crespo M
J Clin Med
. 2016 Jul;
5(7).
PMID: 27420103
Increased vascular angiotensin-converting enzyme (ACE) activity and oxidative stress are present in young Syrian cardiomyopathic hamsters (SCH) before the clinical manifestation of heart failure (HF). The developmental time-course of these...
8.
Martinez N, Ayala A, Martinez M, Martinez-Rivera F, Miranda J, Silva W
J Biol Chem
. 2016 Apr;
291(23):12208-22.
PMID: 27129210
Damage to the CNS can cause a differential spatio-temporal release of multiple factors, such as nucleotides, ATP and UTP. The latter interact with neuronal and glial nucleotide receptors. The P2Y2...
9.
Mosquera L, Shepherd L, Torrado A, Torres-Diaz Y, Miranda J, Segarra A
J Vet Sci Technol
. 2016 Mar;
6(6):276.
PMID: 26962471
Fluctuating sex steroids during the estrous or menstrual cycle of mammalian females make it difficult to determine their role on behaviors and physiology. To avoid this, many investigators ovariectomize their...
10.
Colon J, Torrado A, Cajigas A, Santiago J, Salgado I, Arroyo Y, et al.
J Neurotrauma
. 2016 Feb;
33(18):1696-708.
PMID: 26896212
Spinal cord injury (SCI) is a condition with no available cure. The initial physical impact triggers a cascade of molecular and cellular events that generate a nonpermissive environment for cell...