Scott R Whittemore
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Explore the profile of Scott R Whittemore including associated specialties, affiliations and a list of published articles.
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104
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2472
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Recent Articles
1.
Saraswat Ohri S, Myers S, Rood B, Brown B, Chilton P, Slomnicki L, et al.
Glia
. 2025 Jan;
PMID: 39760211
Cellular stressors inhibit general protein synthesis while upregulating stress response transcripts and/or proteins. Phosphorylation of the translation factor eIF2α by one of the several stress-activated kinases is a trigger for...
2.
Chilton P, Ghare S, Charpentier B, Myers S, Rao A, Petrosino J, et al.
Gut Microbes
. 2024 Aug;
16(1):2389319.
PMID: 39182227
Alterations in the gut-microbiome-brain axis are increasingly being recognized to be involved in Alzheimer's disease (AD) pathogenesis. However, the functional consequences of enteric dysbiosis linking gut microbiota and brain pathology...
3.
Gao Y, Slomnicki L, Kilanczyk E, Forston M, Pietrzak M, Rouchka E, et al.
ASN Neuro
. 2024 Jul;
16(1):2371162.
PMID: 39024571
Endoplasmic reticulum (ER) stress in oligodendrocyte (OL) linage cells contributes to several CNS pathologies including traumatic spinal cord injury (SCI) and multiple sclerosis. Therefore, primary rat OL precursor cell (OPC)...
4.
Saraswat Ohri S, Forston M, Myers S, Brown B, Andres K, Howard R, et al.
Glia
. 2024 Apr;
72(7):1259-1272.
PMID: 38587137
After spinal cord injury (SCI), re-establishing cellular homeostasis is critical to optimize functional recovery. Central to that response is PERK signaling, which ultimately initiates a pro-apoptotic response if cellular homeostasis...
5.
Shepard C, Brown B, Van Rijswijck M, Zalla R, Burke D, Morehouse J, et al.
Elife
. 2023 Dec;
12.
PMID: 38099572
Spinal locomotor circuitry is comprised of rhythm generating centers, one for each limb, that are interconnected by local and long-distance propriospinal neurons thought to carry temporal information necessary for interlimb...
6.
Brown B, Anil N, States G, Whittemore S, Magnuson D
Exp Neurol
. 2023 Dec;
373:114631.
PMID: 38070723
Long ascending propriospinal neurons (LAPNs) are a subset of spinal interneurons that provide direct connectivity between distant spinal segments. Here, we focus specifically on an anatomically defined population of "inter-enlargement"...
7.
Forston M, Wei G, Chariker J, Stephenson T, Andres K, Glover C, et al.
Sci Rep
. 2023 Dec;
13(1):21254.
PMID: 38040794
Reducing the loss of oligodendrocytes (OLs) is a major goal for neuroprotection after spinal cord injury (SCI). Therefore, the OL translatome was determined in Ribotag:Plp1-CreERT2 mice at 2, 10, and...
8.
Forston M, Wei G, Chariker J, Stephenson T, Andres K, Glover C, et al.
Res Sq
. 2023 Aug;
PMID: 37546871
Reducing the loss of oligodendrocytes (OLs) is a major goal for neuroprotection after spinal cord injury (SCI). Therefore, the OL translatome was determined in Ribotag:Plp1-CreERT2 mice at 2, 10, and...
9.
Gao Y, Wei G, Forston M, Rood B, Hodges E, Burke D, et al.
Sci Rep
. 2023 Jun;
13(1):9193.
PMID: 37280306
The integrated stress response (ISR)-activated transcription factors ATF4 and CHOP/DDIT3 may regulate oligodendrocyte (OL) survival, tissue damage and functional impairment/recovery in white matter pathologies, including traumatic spinal cord injury (SCI)....
10.
Ugiliweneza B, Boakye M, Saraswat Ohri S, Whittemore S, Hetman M
J Neurotrauma
. 2023 Jan;
40(17-18):1959-1969.
PMID: 36628481
Circadian rhythms play a role in time-of-day differences in risk, presenting severity and outcomes of stroke. Injury time-of-day effects, however, on occurrence, presenting severity and acute hospital outcomes have not...