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Iris K Salgado

Explore the profile of Iris K Salgado including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 39
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Recent Articles
1.
Colon-Mercado J, Torrado-Tapias A, Salgado I, Santiago J, Rivera S, Bracho-Rincon D, et al.
Neural Regen Res . 2024 Sep; 20(11):3317-3329. PMID: 39314150
JOURNAL/nrgr/04.03/01300535-202511000-00033/figure1/v/2024-12-20T164640Z/r/image-tiff In addition to the loss of motor function, ~ 60% of patients develop pain after spinal cord injury. The cellular-molecular mechanisms are not well understood, but the data suggests...
2.
Colon J, Gonzalez P, Cajigas A, Maldonado W, Torrado A, Santiago J, et al.
Exp Neurol . 2017 Oct; 299(Pt A):109-121. PMID: 29037533
No treatment is available for patients with spinal cord injury (SCI). Patients often arrive to the hospital hours after SCI suggesting the need of a therapy that can be used...
3.
Colon J, Torrado A, Cajigas A, Santiago J, Salgado I, Arroyo Y, et al.
J Neurotrauma . 2016 Feb; 33(18):1696-708. PMID: 26896212
Spinal cord injury (SCI) is a condition with no available cure. The initial physical impact triggers a cascade of molecular and cellular events that generate a nonpermissive environment for cell...
4.
Salgado I, Torrado A, Santiago J, Miranda J
Neural Regen Res . 2015 Apr; 10(3):385-90. PMID: 25878585
Spinal cord injury (SCI) is a devastating condition that produces significant changes in the lifestyle of patients. Many molecular and cellular events are triggered after the initial physical impact to...
5.
Rosas O, Torrado A, Santiago J, Rodriguez A, Salgado I, Miranda J
Neural Regen Res . 2015 Feb; 9(24):2164-73. PMID: 25657738
The spinal cord has the ability to regenerate but the microenvironment generated after trauma reduces that capacity. An increase in Src family kinase (SFK) activity has been implicated in neuropathological...
6.
Santiago J, Torrado A, Arocho L, Rosas O, Rodriguez A, Toro F, et al.
J Mol Neurosci . 2012 Aug; 49(2):347-59. PMID: 22878913
Some receptors that block axonal regeneration or promote cell death after spinal cord injury (SCI) are localized in membrane rafts. Flotillin-2 (Flot-2) is an essential protein associated with the formation...
7.
Salgado I, Serrano M, Garcia J, Martinez N, Maldonado H, Baez-Pagan C, et al.
Cell Mol Neurobiol . 2011 Dec; 32(3):409-21. PMID: 22127416
SorLA is an established sorting and trafficking protein in neurons with demonstrated relevance to Alzheimer's disease (AD). It shares these roles with the caveolins, markers of membrane rafts microdomains. To...