Jorg Hackermuller
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Explore the profile of Jorg Hackermuller including associated specialties, affiliations and a list of published articles.
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64
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6954
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Recent Articles
1.
Canzler S, Schubert K, Rolle-Kampczyk U, Wang Z, Schreiber S, Seitz H, et al.
Arch Toxicol
. 2024 Oct;
99(1):309-332.
PMID: 39441382
Multi-omics data integration has been repeatedly discussed as the way forward to more comprehensively cover the molecular responses of cells or organisms to chemical exposure in systems toxicology and regulatory...
2.
Aldehoff A, Karkossa I, Goerdeler C, Krieg L, Schor J, Engelmann B, et al.
iScience
. 2024 Jun;
27(6):109711.
PMID: 38840842
Obesity, characterized by enlarged and dysfunctional adipose tissue, is among today's most pressing global public health challenges with continuously increasing prevalence. Despite the importance of post-translational protein modifications (PTMs) in...
3.
Kramer L, Schulze T, Kluver N, Altenburger R, Hackermuller J, Krauss M, et al.
Sci Data
. 2024 Jan;
11(1):60.
PMID: 38200014
Chemicals in the aquatic environment can be harmful to organisms and ecosystems. Knowledge on effect concentrations as well as on mechanisms and modes of interaction with biological molecules and signaling...
4.
Soulios K, Scheibe P, Bernt M, Hackermuller J, Schor J
Bioinformatics
. 2023 Nov;
39(12).
PMID: 38011648
Summary: Sophisticated approaches for the in silico prediction of toxicity are required to support the risk assessment of chemicals. The number of chemicals on the global chemical market and the...
5.
Carido M, Volkner M, Steinheuer L, Wagner F, Kurth T, Dumler N, et al.
Front Cell Neurosci
. 2023 Oct;
17:1166641.
PMID: 37868194
The possible applications for human retinal organoids (HROs) derived from human induced pluripotent stem cells (hiPSC) rely on the robustness and transferability of the methodology for their generation. Standardized strategies...
6.
Beckers L, Altenburger R, Brack W, Escher B, Hackermuller J, Hassold E, et al.
Environ Int
. 2023 Sep;
179:108155.
PMID: 37688808
Aquatic environments are polluted with a multitude of organic micropollutants, which challenges risk assessment due the complexity and diversity of pollutant mixtures. The recognition that certain source-specific background pollution occurs...
7.
Wang Z, Haange S, Haake V, Huisinga M, Kamp H, Buesen R, et al.
Metabolites
. 2023 Jul;
13(7).
PMID: 37512556
The thyroid hormones (THs) regulate various physiological mechanisms in mammals, such as cellular metabolism, cell structure, and membrane transport. The therapeutic drugs propylthiouracil (PTU) and phenytoin are known to induce...
8.
Volkner M, Wagner F, Steinheuer L, Carido M, Kurth T, Yazbeck A, et al.
Nat Commun
. 2022 Oct;
13(1):6183.
PMID: 36261438
Human organoids could facilitate research of complex and currently incurable neuropathologies, such as age-related macular degeneration (AMD) which causes blindness. Here, we establish a human retinal organoid system reproducing several...
9.
Schor J, Scheibe P, Bernt M, Busch W, Lai C, Hackermuller J
Brief Bioinform
. 2022 Jul;
23(5).
PMID: 35849097
Many chemicals are present in our environment, and all living species are exposed to them. However, numerous chemicals pose risks, such as developing severe diseases, if they occur at the...
10.
Scholz S, Brack W, Escher B, Hackermuller J, Liess M, von Bergen M, et al.
Arch Toxicol
. 2022 May;
96(8):2381-2386.
PMID: 35543751
No abstract available.