Jordan S Shafran
Overview
Explore the profile of Jordan S Shafran including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
129
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0
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Recent Articles
1.
Mori J, Shafran J, Stojanova M, Katz M, Gignac G, Wisco J, et al.
Prostate
. 2022 Apr;
82(10):1005-1015.
PMID: 35403746
In patients with prostate cancer, the duration of remission after treatment with androgen deprivation therapies (ADTs) varies dramatically. Clinical experience has demonstrated difficulties in predicting individual risk for progression due...
2.
Jafari N, Kolla M, Meshulam T, Shafran J, Qiu Y, Casey A, et al.
Sci Signal
. 2021 Nov;
14(710):eabj2807.
PMID: 34813359
Obesity and metabolic diseases, such as insulin resistance and type 2 diabetes (T2D), are associated with metastatic breast cancer in postmenopausal women. Here, we investigated the critical cellular and molecular...
3.
Shafran J, Jafari N, Casey A, Gyorffy B, Denis G
Prostate Cancer Prostatic Dis
. 2020 Jul;
24(1):268-277.
PMID: 32690869
Background: Androgen deprivation therapies for the hormone-dependent stages of prostate cancer have become so effective that new forms of chemoresistant tumors are emerging in clinical practice, and require new targeted...
4.
Andrieu G, Shafran J, Smith C, Belkina A, Casey A, Jafari N, et al.
Cancer Lett
. 2019 Sep;
465:45-58.
PMID: 31473251
Therapeutic strategies aiming to leverage anti-tumor immunity are being intensively investigated as they show promising results in cancer therapy. The PD-1/PD-L1 pathway constitutes an important target to restore functional anti-tumor...
5.
Shafran J, Andrieu G, Gyorffy B, Denis G
Mol Cancer Res
. 2019 May;
17(8):1627-1638.
PMID: 31110158
The inevitable progression of advanced prostate cancer to castration resistance, and ultimately to lethal metastatic disease, depends on primary or acquired resistance to conventional androgen deprivation therapy (ADT) and accumulated...
6.
Andrieu G, Shafran J, Deeney J, Bharadwaj K, Rangarajan A, Denis G
J Leukoc Biol
. 2018 Mar;
104(2):265-274.
PMID: 29493812
Obesity and its associated pathology Type 2 diabetes are two chronic metabolic and inflammatory diseases that promote breast cancer progression, metastasis, and poor outcomes. Emerging critical opinion considers unresolved inflammation...