JooYeon Engelen-Lee
Overview
Explore the profile of JooYeon Engelen-Lee including associated specialties, affiliations and a list of published articles.
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10
Citations
314
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Recent Articles
1.
Koopmans M, Engelen-Lee J, Brouwer M, Jaspers V, Man W, Vall Seron M, et al.
J Neuroinflammation
. 2018 Sep;
15(1):257.
PMID: 30193592
Background: Listeria monocytogenes is a common cause of bacterial meningitis. We developed an animal model of listerial meningitis. Methods: In survival studies, C57BL/6 mice received intracisternal injections with different L....
2.
Engelen-Lee J, Blokhuis A, Spliet W, Pasterkamp R, Aronica E, Demmers J, et al.
Amyotroph Lateral Scler Frontotemporal Degener
. 2016 Dec;
18(3-4):210-220.
PMID: 27899032
Background: We aimed to gain new insights into the pathogenesis of sporadic ALS (sALS) through a comprehensive proteomic analysis. Methods: Protein profiles of the anterior and posterior horn in post-mortem...
3.
Duitman J, Valls Seron M, Engelen-Lee J, Brouwer M, Spek C, van de Beek D
BMC Infect Dis
. 2016 Nov;
16(1):670.
PMID: 27835970
Background: The most frequent pathogen that causes bacterial meningitis is the Gram-positive bacterium Streptococcus (S.) pneumoniae. CCAAT/enhancer binding protein δ is a transcription factor that has recently been hypothesized to...
4.
Jim K, Engelen-Lee J, van der Sar A, Bitter W, Brouwer M, van der Ende A, et al.
J Neuroinflammation
. 2016 Aug;
13(1):188.
PMID: 27542968
Background: Streptococcus pneumoniae is one of the most important causes of bacterial meningitis, an infection where unfavourable outcome is driven by bacterial and host-derived toxins. In this study, we developed...
5.
Valls Seron M, Ferwerda B, Engelen-Lee J, Geldhoff M, Jaspers V, Zwinderman A, et al.
Acta Neuropathol Commun
. 2016 May;
4(1):50.
PMID: 27193124
Pneumococcal meningitis is the most common and severe form of bacterial meningitis. Fatality rates are substantial, and long-term sequelae develop in about half of survivors. Here, we have performed a...
6.
Valls Seron M, Duitman J, Geldhoff M, Engelen-Lee J, Havik S, Brouwer M, et al.
J Neuroinflammation
. 2015 May;
12:88.
PMID: 25958220
Background: The prognosis of bacterial meningitis largely depends on the severity of the inflammatory response. The transcription factor CAAT/enhancer-binding protein δ (C/EBPδ) plays a key role in the regulation of...
7.
Groen E, Fumoto K, Blokhuis A, Engelen-Lee J, Zhou Y, van den Heuvel D, et al.
Hum Mol Genet
. 2013 May;
22(18):3690-704.
PMID: 23681068
Mutations in the RNA binding protein fused in sarcoma/translated in liposarcoma (FUS/TLS) cause amyotrophic lateral sclerosis (ALS). Although ALS-linked mutations in FUS often lead to a cytosolic mislocalization of the...
8.
van Veluw S, Zwanenburg J, Engelen-Lee J, Spliet W, Hendrikse J, Luijten P, et al.
J Cereb Blood Flow Metab
. 2012 Dec;
33(3):322-9.
PMID: 23250109
Cerebrovascular disease has an important role in cognitive decline and dementia. In this context, cerebral microinfarcts are attracting increasing attention, but these lesions could thus far not be detected in...
9.
Koppers M, van Blitterswijk M, Vlam L, Rowicka P, van Vught P, Groen E, et al.
Neurobiol Aging
. 2011 Nov;
33(4):837.e7-13.
PMID: 22078486
Mutations in the valosin-containing protein (VCP) gene were recently reported to be the cause of 1%-2% of familial amyotrophic lateral sclerosis (ALS) cases. VCP mutations are known to cause inclusion...
10.
Broekman M, Risselada R, Engelen-Lee J, Spliet W, Verweij B
Case Rep Med
. 2009 Dec;
2009:757898.
PMID: 20029672
Patients with Neurofibromatosis type 1 (NF1) have an increased risk of developing neoplasms. The most common brain tumors, found in 15%-20% of NF1 patients, are hypothalamic-optic gliomas, followed by brainstem...