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Joost P M van Meerwijk

Explore the profile of Joost P M van Meerwijk including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 898
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Recent Articles
1.
Santamaria J, Vuillier S, Galindo-Albarran A, Castan S, Detraves C, Joffre O, et al.
Front Immunol . 2024 Feb; 15:1358459. PMID: 38404576
Regulatory T lymphocytes expressing the transcription factor Foxp3 (Tregs) play an important role in the prevention of autoimmune diseases and other immunopathologies. Aberrations in Treg-mediated immunosuppression are therefore thought to...
2.
Apert C, Galindo-Albarran A, Castan S, Detraves C, Michaud H, McJannett N, et al.
Front Immunol . 2022 Sep; 13:965303. PMID: 36159793
Development of Foxp3-expressing regulatory T-lymphocytes (Treg) in the thymus is controlled by signals delivered in T-cell precursors the TCR, co-stimulatory receptors, and cytokine receptors. In absence of IL-2, IL-15 or...
3.
Galindo-Albarran A, Castan S, Santamaria J, Joffre O, Haegeman B, Romagnoli P, et al.
Diabetes . 2021 May; 70(8):1729-1737. PMID: 34035042
Regulatory T lymphocytes expressing the forkhead/winged helix transcription factor Foxp3 (Treg) play a vital role in the protection of the organism from autoimmune disease and other immunopathologies. The antigen specificity...
4.
Darrigues J, Santamaria J, Galindo-Albarran A, Robey E, Joffre O, van Meerwijk J, et al.
Eur J Immunol . 2020 Jul; 51(3):580-593. PMID: 32730634
Regulatory T lymphocytes (Treg) play a vital role in the protection of the organism against autoimmune pathology. It is therefore paradoxical that comparatively large numbers of Treg were found in...
5.
Adoue V, Binet B, Malbec A, Fourquet J, Romagnoli P, van Meerwijk J, et al.
Immunity . 2019 Feb; 50(3):629-644.e8. PMID: 30737147
Upon activation, naive CD4 T cells differentiate into distinct T cell subsets via processes reliant on epigenetically regulated, lineage-specific developmental programs. Here, we examined the function of the histone methyltransferase...
6.
Santamaria J, Darrigues J, van Meerwijk J, Romagnoli P
Immunol Lett . 2018 Oct; 204:9-15. PMID: 30308217
Hematopoietic precursors entering the thymus undergo a maturation process leading to the generation of a variety of T cell subsets that migrate to the periphery to perform their effector functions....
7.
Darrigues J, van Meerwijk J, Romagnoli P
Gerontology . 2017 Jul; 64(1):28-35. PMID: 28704827
The generation and function of immuno-suppressive regulatory T lymphocytes (Treg), which can differentiate in the thymus (tTreg) or in the periphery (pTreg), are regulated in an age-dependent manner. tTreg are...
8.
Apert C, Romagnoli P, van Meerwijk J
Protein Cell . 2017 May; 9(4):322-332. PMID: 28540653
Immunosuppressive regulatory T lymphocytes (Treg) expressing the transcription factor Foxp3 play a vital role in the maintenance of tolerance of the immune-system to self and innocuous non-self. Most Treg that...
9.
Vuddamalay Y, van Meerwijk J
Front Immunol . 2017 Feb; 8:31. PMID: 28167946
Since the rebirth of regulatory (formerly known as suppressor) T cells in the early 1990s, research in the field of immune-regulation by various T cell populations has quickly gained momentum....
10.
Vuddamalay Y, Attia M, Vicente R, Pomie C, Enault G, Leobon B, et al.
Immunology . 2016 Mar; 148(2):187-96. PMID: 26924728
Regulatory T (Treg) lymphocytes play a central role in the control of immune responses and so maintain immune tolerance and homeostasis. In mice, expression of the CD8 co-receptor and low...