Joost H van Delft
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Explore the profile of Joost H van Delft including associated specialties, affiliations and a list of published articles.
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11
Citations
104
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Recent Articles
1.
Hebels D, Jetten M, Aerts H, Herwig R, Theunissen D, Gaj S, et al.
Biomark Med
. 2014 Feb;
8(2):185-200.
PMID: 24521014
Current testing models for predicting drug-induced liver injury are inadequate, as they basically under-report human health risks. We present here an approach towards developing pathways based on hepatotoxicity-associated gene groups...
2.
Limonciel A, Wilmes A, Aschauer L, Radford R, Bloch K, McMorrow T, et al.
Arch Toxicol
. 2012 Jul;
86(11):1741-51.
PMID: 22760423
Potassium bromate (KBrO(3)) is an oxidising agent that has been widely used in the food and cosmetic industries. It has shown to be both a nephrotoxin and a renal carcinogen...
3.
Lizarraga D, Vinardell M, Noe V, van Delft J, Alcarraz-Vizan G, Van Breda S, et al.
J Nutr
. 2011 Jul;
141(9):1597-604.
PMID: 21775529
Diet plays a decisive role in promoting or preventing colon cancer. However, the specific effects of some nutrients remain unclear. The capacity of fruit and vegetables to prevent cancer has...
4.
van Kesteren P, Zwart P, Pennings J, Gottschalk W, Kleinjans J, van Delft J, et al.
Toxicol Sci
. 2011 Jul;
123(1):123-32.
PMID: 21715664
The current method to predict carcinogenicity of chemicals or drugs is the chronic 2-year rodent bioassay, which has disadvantages in duration, animal use, and specificity. An attractive alternative is the...
5.
van Dartel D, Pennings J, De La Fonteyne L, Brauers K, Claessen S, van Delft J, et al.
Toxicol Appl Pharmacol
. 2011 Jan;
251(2):110-8.
PMID: 21192963
The murine embryonic stem cell test (EST) is designed to evaluate developmental toxicity based on compound-induced inhibition of embryonic stem cell (ESC) differentiation into cardiomyocytes. The addition of transcriptomic evaluation...
6.
van Dartel D, Pennings J, De La Fonteyne L, Brauers K, Claessen S, van Delft J, et al.
Toxicol Sci
. 2010 Oct;
119(1):126-34.
PMID: 20935163
The murine embryonic stem cell test (EST) is an alternative testing method designed to assess potential developmental toxicity of compounds. The implementation of transcriptomics in the EST has been shown...
7.
van Dartel D, Pennings J, De La Fonteyne L, van Herwijnen M, van Delft J, van Schooten F, et al.
Toxicol Sci
. 2010 Apr;
116(1):130-9.
PMID: 20421339
The embryonic stem cell test (EST) has been designed to predict developmental toxicity based upon compound-induced inhibition of embryonic stem cell (ESC) differentiation. The end point scoring, the test duration,...
8.
Lizarraga D, Tourino S, Reyes-Zurita F, de Kok T, van Delft J, Maas L, et al.
J Agric Food Chem
. 2008 Nov;
56(24):11675-82.
PMID: 19035659
Witch hazel (Hamamelis virginia) extracts are used in traditional medicine. They are particularly rich in gallate esters included in proanthocyanidins, hydrolyzable tannins (galloylated sugars), and methyl gallate. This study examines...
9.
Van Breda S, Hogervorst J, Schouten L, Knaapen A, van Delft J, Goldbohm R, et al.
Clin Chem
. 2007 May;
53(6):1168-70.
PMID: 17517594
No abstract available.
10.
Corvi R, Ahr H, Albertini S, Blakey D, Clerici L, Coecke S, et al.
Environ Health Perspect
. 2006 Mar;
114(3):420-9.
PMID: 16507466
This is the report of the first workshop "Validation of Toxicogenomics-Based Test Systems" held 11-12 December 2003 in Ispra, Italy. The workshop was hosted by the European Centre for the...