Jongkyu Choi
Overview
Explore the profile of Jongkyu Choi including associated specialties, affiliations and a list of published articles.
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29
Citations
711
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Recent Articles
11.
Choi J, Dixon D, Dansithong W, Abdallah W, Roos K, Jordan M, et al.
Sci Rep
. 2016 Aug;
6:30999.
PMID: 27484195
Myotonic dystrophy type I (DM1) exhibits distinctive disease specific phenotypes and the accelerated onset of a spectrum of age-associated pathologies. In DM1, dominant effects of expanded CUG repeats result in...
12.
Choi J, Personius K, DiFranco M, Dansithong W, Yu C, Srivastava S, et al.
EBioMedicine
. 2015 Oct;
2(9):1034-47.
PMID: 26501102
Research In Context: Research in context: Myotonic Dystrophy type 1 (DM1) is a dominant disorder resulting from the expression of expanded CUG repeat RNA, which aberrantly sequesters and inactivates the...
13.
Loss of muscleblind-like 1 results in cardiac pathology and persistence of embryonic splice isoforms
Dixon D, Choi J, El-Ghazali A, Park S, Roos K, Jordan M, et al.
Sci Rep
. 2015 Mar;
5:9042.
PMID: 25761764
Cardiac dysfunction is a prominent cause of mortality in myotonic dystrophy I (DM1), a disease where expanded CUG repeats bind and disable the muscleblind-like family of splice regulators. Deletion of...
14.
Kim K, Lee B, Kim J, Choi J, Kim J, Xiong Y, et al.
Cell Rep
. 2013 Dec;
5(6):1690-703.
PMID: 24360965
Increasing evidence suggests that linker histone H1 can influence distinct cellular processes by acting as a gene-specific regulator. However, the mechanistic basis underlying such H1 specificity and whether H1 acts...
15.
Kim K, Punj V, Choi J, Heo K, Kim J, Laird P, et al.
Epigenetics Chromatin
. 2013 Nov;
6(1):34.
PMID: 24279307
Background: The incorporation of histone variants into nucleosomes is one of the main strategies that the cell uses to regulate the structure and function of chromatin. Histone H2A.Z is an...
16.
Kim K, Kim J, Kim J, Choi J, Suk Lee Y, Neamati N, et al.
Mol Cell
. 2013 Oct;
52(3):459-67.
PMID: 24140421
Histone modifications play important roles in the regulation of gene expression and chromatin organization. VprBP has been implicated in transcriptionally silent chromatin formation and cell-cycle regulation, but the molecular basis...
17.
Kim K, Heo K, Choi J, Jackson S, Kim H, Xiong Y, et al.
Mol Cell Biol
. 2011 Dec;
32(4):783-96.
PMID: 22184063
HIV-1 Vpr-binding protein (VprBP) has been implicated in the regulation of both DNA replication and cell cycle progression, but its precise role remains unclear. Here we report that VprBP regulates...
18.
Kim H, Kim K, Choi J, Heo K, Baek H, Roeder R, et al.
J Mol Biol
. 2011 Dec;
415(5):843-54.
PMID: 22178617
The tumor suppressor p53 plays a critical role in mediating cellular response to a wide range of environmental stresses. p53 regulates these processes mainly by acting as a short-lived DNA...
19.
Choi J, Kim H, Kim K, Lee B, Lu W, An W
Nucleic Acids Res
. 2011 Aug;
39(21):9167-80.
PMID: 21846774
The N-terminal tail of histone H2B is believed to be involved in gene silencing, but how it exerts its function remains elusive. Here, we report the biochemical characterization of p14ARF...
20.
Kim H, Heo K, Choi J, Kim K, An W
Nucleic Acids Res
. 2011 Jul;
39(19):8329-41.
PMID: 21742762
Histone variant H3.3 and heterochromatin protein 1γ (HP1γ) are two functional components of chromatin with role in gene transcription. However, the regulations of their dynamics during transcriptional activation and the...