Jonathan V Sweedler
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Explore the profile of Jonathan V Sweedler including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Andersen H, Tai H, Rubakhin S, Yau P, Sweedler J
J Biol Chem
. 2024 Jun;
300(7):107458.
PMID: 38857862
The function of endogenous cell-cell signaling peptides relies on their interactions with cognate receptors, which in turn are influenced by the peptides' structures, necessitating a comprehensive understanding of the suite...
12.
Wang Y, Saha U, Rubakhin S, Roy E, Smith A, Sweedler J, et al.
NMR Biomed
. 2024 May;
37(10):e5161.
PMID: 38715469
Achieving high-resolution and high signal-to-noise ratio (SNR) in vivo metabolic imaging via fast magnetic resonance spectroscopic imaging (MRSI) has been a longstanding challenge. This study combines the methods of relaxation...
13.
Huang K, Upadhyay G, Ahn Y, Sakakura M, Pagan-Diaz G, Cho Y, et al.
Proc Natl Acad Sci U S A
. 2024 Apr;
121(19):e2313590121.
PMID: 38683978
Myokines and exosomes, originating from skeletal muscle, are shown to play a significant role in maintaining brain homeostasis. While exercise has been reported to promote muscle secretion, little is known...
14.
Okyem S, Romanova E, Tai H, Checco J, Sweedler J
Methods Mol Biol
. 2024 Mar;
2758:227-240.
PMID: 38549017
D-amino acid-containing peptides (DAACPs) in animals are a class of bioactive molecules formed via the posttranslational modification of peptides consisting of all-L-amino acid residues. Amino acid residue isomerization greatly impacts...
15.
Southey B, Romanova E, Rodriguez-Zas S, Sweedler J
Methods Mol Biol
. 2024 Mar;
2758:151-178.
PMID: 38549013
Neuropeptides and peptide hormones are signaling molecules produced via complex posttranslational modifications of precursor proteins known as prohormones. Neuropeptides activate specific receptors and are associated with the regulation of physiological...
16.
Su P, Hollas M, Butun F, Kanchustambham V, Rubakhin S, Ramani N, et al.
J Proteome Res
. 2024 Mar;
23(6):1883-1893.
PMID: 38497708
We introduce single cell Proteoform imaging Mass Spectrometry (), which realizes the benefit of direct solvent extraction and MS detection of intact proteins from single cells dropcast onto glass slides....
17.
Xie Y, Castro D, Rubakhin S, Trinklein T, Sweedler J, Lam F
Nat Methods
. 2024 Feb;
21(3):521-530.
PMID: 38366241
Spatial omics technologies can reveal the molecular intricacy of the brain. While mass spectrometry imaging (MSI) provides spatial localization of compounds, comprehensive biochemical profiling at a brain-wide scale in three...
18.
Parmar D, Rosado-Rosa J, Shrout J, Sweedler J
Methods
. 2024 Jan;
224:21-34.
PMID: 38295894
Biofilms are dense aggregates of bacterial colonies embedded inside a self-produced polymeric matrix. Biofilms have received increasing attention in medical, industrial, and environmental settings due to their enhanced survival. Their...
19.
Croslow S, Trinklein T, Sweedler J
FEBS Lett
. 2024 Jan;
598(6):591-601.
PMID: 38243373
Multimodal mass spectrometry (MMS) incorporates an imaging modality with probe-based mass spectrometry (MS) to enable precise, targeted data acquisition and provide additional biological and chemical data not available by MS...
20.
Lee C, Lee D, Wei I, Qiu T, Rubakhin S, Roper M, et al.
ACS Omega
. 2023 Dec;
8(50):47723-47734.
PMID: 38144114
The cell-to-cell signaling role of d-amino acids (d-AAs) in the mammalian endocrine system, particularly in the islets of Langerhans, has drawn growing interest for their potential involvement in modulating glucose...