Jonathan Elegheert
Overview
Explore the profile of Jonathan Elegheert including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
693
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Recent Articles
1.
Ung D, Pietrancosta N, Badillo E, Raux B, Tapken D, Zlatanovic A, et al.
Mol Psychiatry
. 2024 Feb;
29(4):1205-1215.
PMID: 38418578
The ionotropic glutamate delta receptor GluD1, encoded by the GRID1 gene, is involved in synapse formation, function, and plasticity. GluD1 does not bind glutamate, but instead cerebellin and D-serine, which...
2.
Behiels E, Elegheert J
Methods Mol Biol
. 2021 May;
2305:83-104.
PMID: 33950385
Mammalian protein expression systems are ideally suited for the high-level production of recombinant eukaryotic secreted and membrane proteins for structural biology applications. Here, we present genetic transduction of HEK293-derived cells...
3.
Robinson R, Griffiths S, van de Haar L, Malinauskas T, van Battum E, Zelina P, et al.
Cell
. 2021 Mar;
184(8):2103-2120.e31.
PMID: 33740419
During cell migration or differentiation, cell surface receptors are simultaneously exposed to different ligands. However, it is often unclear how these extracellular signals are integrated. Neogenin (NEO1) acts as an...
4.
Elegheert J, Cvetkovska V, Clayton A, Heroven C, Vennekens K, Smukowski S, et al.
Neuron
. 2021 Jan;
109(1):189-190.
PMID: 33412094
No abstract available.
5.
Suzuki K, Elegheert J, Song I, Sasakura H, Senkov O, Matsuda K, et al.
Science
. 2020 Aug;
369(6507).
PMID: 32855309
Neuronal synapses undergo structural and functional changes throughout life, which are essential for nervous system physiology. However, these changes may also perturb the excitatory-inhibitory neurotransmission balance and trigger neuropsychiatric and...
6.
Felix J, De Munck S, Verstraete K, Meuris L, Callewaert N, Elegheert J, et al.
Structure
. 2020 Apr;
28(4):488.
PMID: 32268078
No abstract available.
7.
Connor S, Elegheert J, Xie Y, Craig A
Curr Opin Neurobiol
. 2019 Feb;
57:71-80.
PMID: 30771697
Synapse development depends on a dynamic balance between synapse promoters and suppressors. MDGAs, immunoglobulin superfamily proteins, negatively regulate synapse development through blocking neuroligin-neurexin interactions. Recent analyses of MDGA-neuroligin complexes revealed...
8.
Elegheert J, Behiels E, Bishop B, Scott S, Woolley R, Griffiths S, et al.
Nat Protoc
. 2018 Nov;
13(12):2991-3017.
PMID: 30455477
Structural, biochemical and biophysical studies of eukaryotic soluble and membrane proteins require their production in milligram quantities. Although large-scale protein expression strategies based on transient or stable transfection of mammalian...
9.
Nolan R, Alvarez L, Griffiths S, Elegheert J, Siebold C, Padilla-Parra S
J Vis Exp
. 2018 Aug;
(137).
PMID: 30080195
Number and brightness is a calibration-free fluorescence fluctuation spectroscopy (FFS) technique for detecting protein homo-oligomerization. It can be employed using a conventional confocal microscope equipped with digital detectors. A protocol...
10.
Nolan R, Alvarez L, Elegheert J, Iliopoulou M, Jakobsdottir G, Rodriguez-Munoz M, et al.
Bioinformatics
. 2017 Oct;
33(21):3508-3510.
PMID: 29036562
Summary: An R package for performing number and brightness image analysis, with the implementation of a novel automatic detrending algorithm. Availability And Implementation: Available at https://github.com/rorynolan/nandb for all platforms. Contact:...