Kenneth Verstraete
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Explore the profile of Kenneth Verstraete including associated specialties, affiliations and a list of published articles.
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35
Citations
750
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Recent Articles
1.
Semwal S, Karamolegkou M, Flament S, Raouraoua N, Verstraete K, Thureau A, et al.
Acta Crystallogr F Struct Biol Commun
. 2024 Dec;
81(Pt 1):19-29.
PMID: 39718025
Monoclonal antibodies recognizing nonprotein antigens remain largely underrepresented in our understanding of the molecular repertoire of innate and adaptive immunity. One such antibody is Mannitou, a murine IgM that recognizes...
2.
Heyndrickx I, Deswarte K, Verstraete K, Verschueren K, Smole U, Aegerter H, et al.
Elife
. 2024 Jan;
12.
PMID: 38194250
Spontaneous protein crystallization is a rare event, yet protein crystals are frequently found in eosinophil-rich inflammation. In humans, Charcot-Leyden crystals (CLCs) are made from galectin-10 (Gal10) protein, an abundant protein...
3.
Swinnen K, Verstraete K, Baratto C, Hardy L, De Vos M, Topalovic M, et al.
ERJ Open Res
. 2023 Sep;
9(5).
PMID: 37727672
Background And Aims: Pulmonary hypertension due to left heart disease (PH-LHD) is the most frequent form of PH. As differential diagnosis with pulmonary arterial hypertension (PAH) has therapeutic implications, it...
4.
Funcke J, Moepps B, Roos J, von Schnurbein J, Verstraete K, Frohlich-Reiterer E, et al.
N Engl J Med
. 2023 Jun;
388(24):2253-2261.
PMID: 37314706
Hormone absence or inactivity is common in congenital disease, but hormone antagonism remains controversial. Here, we characterize two novel homozygous leptin variants that yielded antagonistic proteins in two unrelated children...
5.
Verstraete K, Gyselinck I, Huts H, Das N, Topalovic M, De Vos M, et al.
Thorax
. 2023 Apr;
78(10):983-989.
PMID: 37012070
Rationale: Estimating the causal effect of an intervention at individual level, also called individual treatment effect (ITE), may help in identifying response prior to the intervention. Objectives: We aimed to...
6.
Tsirigotaki A, Dansercoer A, Verschueren K, Markovic I, Pollmann C, Hafer M, et al.
Nat Struct Mol Biol
. 2023 Mar;
30(4):551-563.
PMID: 36959263
The adipokine Leptin activates its receptor LEP-R in the hypothalamus to regulate body weight and exerts additional pleiotropic functions in immunity, fertility and cancer. However, the structure and mechanism of...
7.
Verstraete K, Das N, Gyselinck I, Topalovic M, Troosters T, Crapo J, et al.
Respir Res
. 2023 Jan;
24(1):20.
PMID: 36658542
Background: Parameters from maximal expiratory flow-volume curves (MEFVC) have been linked to CT-based parameters of COPD. However, the association between MEFVC shape and phenotypes like emphysema, small airways disease (SAD)...
8.
Arroyo-Hornero R, Aegerter H, Hamad I, Corte-Real B, Staes K, van der Woning B, et al.
Allergy
. 2022 May;
77(9):2818-2821.
PMID: 35491437
No abstract available.
9.
Cao L, Coventry B, Goreshnik I, Huang B, Sheffler W, Park J, et al.
Nature
. 2022 Mar;
605(7910):551-560.
PMID: 35332283
The design of proteins that bind to a specific site on the surface of a target protein using no information other than the three-dimensional structure of the target remains a...
10.
Mohamed S, Wohlmann A, Schofield P, Sia K, McCalmont H, Savvides S, et al.
Int J Biol Macromol
. 2021 Sep;
190:214-223.
PMID: 34481852
Antibody fragments are promising building blocks for developing targeted therapeutics, thus improving treatment efficacy while minimising off-target toxicity. Despite recent advances in targeted therapeutics, patients with Philadelphia-like acute lymphoblastic leukemia...