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Jonathan D Gruber

Explore the profile of Jonathan D Gruber including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 437
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Recent Articles
11.
Wolford J, Colligan P, Gruber J, Bogardus C
Mol Genet Metab . 2003 Dec; 80(3):338-43. PMID: 14680981
Circulating levels of the cytokine interleukin 6 (IL-6) are elevated in obesity, correlate with body mass index (BMI), and predict the development of type 2 diabetes mellitus (T2DM). A promoter...
12.
Wolford J, Gruber J, Ossowski V, Vozarova B, Tataranni P, Bogardus C, et al.
Mol Genet Metab . 2003 Mar; 78(2):136-44. PMID: 12618085
Linkage analysis has identified a susceptibility locus for type 2 diabetes mellitus (T2DM) on chromosome 1q21-q23 in several populations. Results from recent prospective studies indicate that increased levels of C-reactive...
13.
Vozarova B, Fernandez-Real J, Knowler W, Gallart L, Hanson R, Gruber J, et al.
Hum Genet . 2003 Feb; 112(4):409-13. PMID: 12589429
Chronic low-grade activation of the immune system may play a role in the pathogenesis of type-2 diabetes mellitus (T2DM). Interleukin-6 (IL6), a powerful inducer of hepatic acute phase response, has...
14.
Gruber J, Colligan P, Wolford J
Hum Genet . 2002 Jun; 110(5):395-401. PMID: 12073008
Positional cloning of genes underlying complex diseases, such as type 2 diabetes mellitus (T2DM), typically follows a two-tiered process in which a chromosomal region is first identified by genome-wide linkage...