Jonas R Knudsen
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Explore the profile of Jonas R Knudsen including associated specialties, affiliations and a list of published articles.
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27
Citations
328
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Recent Articles
1.
Li J, Madsen A, Knudsen J, Henriquez-Olguin C, Persson K, Li Z, et al.
FASEB J
. 2025 Jan;
39(2):e70277.
PMID: 39835637
The kinases AMPK, and mTOR as part of either mTORC1 or mTORC2, are major orchestrators of cellular growth and metabolism. Phosphorylation of mTOR Ser1261 is reportedly stimulated by both insulin...
2.
Kristensen J, Kjobsted R, Larsen T, Carl C, Hingst J, Onslev J, et al.
Nat Metab
. 2024 Nov;
6(12):2254-2266.
PMID: 39482542
In the Greenlandic Inuit population, 4% are homozygous carriers of a genetic nonsense TBC1D4 p.Arg684Ter variant leading to loss of the muscle-specific isoform of TBC1D4 and an approximately tenfold increased...
3.
Henriquez-Olguin C, Meneses-Valdes R, Raun S, Gallero S, Knudsen J, Li Z, et al.
Redox Biol
. 2023 Aug;
65:102842.
PMID: 37572454
The production of reactive oxygen species (ROS) by NADPH oxidase (NOX) 2 has been linked to both insulin resistance and exercise training adaptations in skeletal muscle. This study explores the...
4.
Kido K, Eskesen N, Henriksen N, Onslev J, Kristensen J, Larsen M, et al.
Diabetes
. 2023 Jul;
72(10):1397-1408.
PMID: 37506328
Article Highlights: Exercise-induced activation of AMPK in skeletal muscle has been proposed to regulate muscle glucose uptake in recovery from exercise. This study investigated whether the muscle-specific AMPKγ3-associated heterotrimeric complex...
5.
Raun S, Ali M, Han X, Henriquez-Olguin C, Pham T, Meneses-Valdes R, et al.
J Cachexia Sarcopenia Muscle
. 2023 May;
14(4):1631-1647.
PMID: 37194385
Background: Metabolic dysfunction and cachexia are associated with poor cancer prognosis. With no pharmacological treatments, it is crucial to define the molecular mechanisms causing cancer-induced metabolic dysfunction and cachexia. Adenosine...
6.
Knudsen J, Persson K, Henriquez-Olguin C, Li Z, Di Leo N, Hesselager S, et al.
Elife
. 2023 Apr;
12.
PMID: 37073948
Microtubules serve as tracks for long-range intracellular trafficking of glucose transporter 4 (GLUT4), but the role of this process in skeletal muscle and insulin resistance is unclear. Here, we used...
7.
Radeke C, Pons R, Mihajlovic M, Knudsen J, Butdayev S, Kempen P, et al.
ACS Appl Mater Interfaces
. 2023 Jan;
15(2):2564-2577.
PMID: 36598781
For three-dimensional (3D) bioprinting to fulfill its promise and enable the automated fabrication of complex tissue-mimicking constructs, there is a need for developing bioinks that are not only printable and...
8.
Knudsen J, Madsen A, Li Z, Andersen N, Schjerling P, Jensen T
Physiol Rep
. 2022 Feb;
10(4):e15183.
PMID: 35224890
The cortical cytoskeleton, consisting of the cytoplasmic actin isoforms β and/or γ-actin, has been implicated in insulin-stimulated GLUT4 translocation and glucose uptake in muscle and adipose cell culture. Furthermore, transgenic...
9.
Meister J, Bone D, Knudsen J, Barella L, Velenosi T, Akhmedov D, et al.
Nat Commun
. 2022 Jan;
13(1):22.
PMID: 35013148
Activation of the sympathetic nervous system causes pronounced metabolic changes that are mediated by multiple adrenergic receptor subtypes. Systemic treatment with βadrenergic receptor agonists results in multiple beneficial metabolic effects,...
10.
Meister J, Bone D, Knudsen J, Barella L, Liu L, Lee R, et al.
Mol Metab
. 2021 Dec;
55:101415.
PMID: 34883278
Objective: The goal of this study was to determine the glucometabolic effects of acute activation of G signaling in skeletal muscle (SKM) in vivo and its contribution to whole-body glucose...