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Erik A Richter

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Articles 202
Citations 7685
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Recent Articles
1.
Nicolaisen T, Lyster A, Sjoberg K, Haas D, Voldstedlund C, Lundsgaard A, et al.
Nat Metab . 2025 Mar; PMID: 40050437
Dietary protein restriction increases energy expenditure and enhances insulin sensitivity in mice. However, the effects of a eucaloric protein-restricted diet in healthy humans remain unexplored. Here, we show in lean,...
2.
Passini F, Bornstein B, Rubin S, Kuperman Y, Krief S, Masschelein E, et al.
Cell Metab . 2025 Feb; PMID: 39919739
Systemic metabolism ensures energy homeostasis through inter-organ crosstalk regulating thermogenic adipose tissue. Unlike the well-described inductive role of the sympathetic system, the inhibitory signal ensuring energy preservation remains poorly understood....
3.
Van der Stede T, Van de Loock A, Turiel G, Hansen C, Tamariz-Ellemann A, Ullrich M, et al.
Cell Metab . 2025 Feb; PMID: 39919738
Plasticity of skeletal muscle is induced by transcriptional and translational events in response to exercise, leading to multiple health and performance benefits. The skeletal muscle microenvironment harbors myofibers and mononuclear...
4.
Li J, Madsen A, Knudsen J, Henriquez-Olguin C, Persson K, Li Z, et al.
FASEB J . 2025 Jan; 39(2):e70277. PMID: 39835637
The kinases AMPK, and mTOR as part of either mTORC1 or mTORC2, are major orchestrators of cellular growth and metabolism. Phosphorylation of mTOR Ser1261 is reportedly stimulated by both insulin...
5.
Miranda-Cervantes A, Fritzen A, Raun S, Hodek O, Moller L, Johann K, et al.
Nat Commun . 2025 Jan; 16(1):345. PMID: 39746949
Metabolic flexibility in skeletal muscle is essential for maintaining healthy glucose and lipid metabolism, and its dysfunction is closely linked to metabolic diseases. Exercise enhances metabolic flexibility, making it an...
6.
Needham E, Hingst J, Onslev J, Diaz-Vegas A, Leandersson M, Huckstep H, et al.
Cell Metab . 2024 Nov; 36(12):2542-2559.e6. PMID: 39577414
Type 2 diabetes is preceded by a defective insulin response, yet our knowledge of the precise mechanisms is incomplete. Here, we investigate how insulin resistance alters skeletal muscle signaling and...
7.
Kristensen J, Kjobsted R, Larsen T, Carl C, Hingst J, Onslev J, et al.
Nat Metab . 2024 Nov; 6(12):2254-2266. PMID: 39482542
In the Greenlandic Inuit population, 4% are homozygous carriers of a genetic nonsense TBC1D4 p.Arg684Ter variant leading to loss of the muscle-specific isoform of TBC1D4 and an approximately tenfold increased...
8.
Sigvardsen C, Richter M, Engelbeen S, Kleinert M, Richter E
Trends Endocrinol Metab . 2024 Oct; PMID: 39472228
Growth differentiation factor 15 (GDF15) is a member of the transforming growth factor-β (TGF-β) superfamily. Despite its identification over 20 years ago, the functions of GDF15 remain complex and not...
9.
Kanta J, Lundsgaard A, Havelund J, Armour S, Baek O, Nguyen D, et al.
Am J Physiol Endocrinol Metab . 2024 Oct; 328(1):E1-E20. PMID: 39441241
Several health-beneficial effects are associated with intake of medium-chain triacylglycerol (MCT); however, the underlying mechanisms are unknown. Furthermore, it remains uncertain whether the acute metabolic effects of MCT differ between...
10.
Zhang J, Sjoberg K, Gong S, Wang T, Li F, Kuo A, et al.
Cell Metab . 2024 Sep; 36(11):2383-2401.e9. PMID: 39270655
Endothelial cells (ECs) not only form passive blood conduits but actively contribute to nutrient transport and organ homeostasis. The role of ECs in glucose homeostasis is, however, poorly understood. Here,...