Jonas Petersen
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Explore the profile of Jonas Petersen including associated specialties, affiliations and a list of published articles.
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17
Citations
82
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Recent Articles
1.
Petersen J, Johansen V, Clemmensen C
Cell Metab
. 2025 Mar;
37(3):790-790.e1.
PMID: 40043693
Advances in the understanding of homeostatic regulation of body weight and the neurobiology of appetite, combined with innovations in medicinal chemistry, have paved the way for safe and effective weight...
2.
Gross T, Stehle D, Nagel C, Zhou F, Duman E, Hernandez-Olmos V, et al.
Anesthesiology
. 2024 Nov;
142(2):332-348.
PMID: 39503623
Background: Emerging evidence indicates that cyclic nucleotide phosphodiesterases exert distinct functions in pain processing and that targeting phosphodiesterases might be a novel strategy for pain relief. This study hypothesized that...
3.
Petersen J, Merrild C, Lund J, Holm S, Clemmensen C
Mol Metab
. 2024 Sep;
89:102027.
PMID: 39265725
Objectives: The potential benefits of combining lifestyle changes with weight loss pharmacotherapies for obesity treatment are underexplored. Building on recent clinical observations, this study aimed to determine whether "lead-in" calorie...
4.
Petersen J, Ludwig M, Juozaityte V, Ranea-Robles P, Svendsen C, Hwang E, et al.
Nature
. 2024 May;
629(8014):1133-1141.
PMID: 38750368
The N-methyl-D-aspartate (NMDA) receptor is a glutamate-activated cation channel that is critical to many processes in the brain. Genome-wide association studies suggest that glutamatergic neurotransmission and NMDA receptor-mediated synaptic plasticity...
5.
Fadahunsi N, Petersen J, Metz S, Jakobsen A, Vad Mathiesen C, Silke Buch-Rasmussen A, et al.
Sci Adv
. 2024 Mar;
10(9):eadg2636.
PMID: 38427737
Human genome-wide association studies (GWAS) suggest a functional role for central glutamate receptor signaling and plasticity in body weight regulation. Here, we use UK Biobank GWAS summary statistics of body...
6.
Falk S, Petersen J, Svendsen C, Romero-Leguizamon C, Jorgensen S, Krauth N, et al.
Cell Rep
. 2023 May;
42(5):112466.
PMID: 37148870
Glucagon-like peptide-1 receptor (GLP-1R) agonists promote nicotine avoidance. Here, we show that the crosstalk between GLP-1 and nicotine extends beyond effects on nicotine self-administration and can be exploited pharmacologically to...
7.
Flauaus C, Engel P, Zhou F, Petersen J, Ruth P, Lukowski R, et al.
Anesthesiology
. 2022 Mar;
136(5):802-822.
PMID: 35303056
Background: Slick, a sodium-activated potassium channel, has been recently identified in somatosensory pathways, but its functional role is poorly understood. The authors of this study hypothesized that Slick is involved...
8.
Bavo F, de-Jong H, Petersen J, Falk-Petersen C, Loffler R, Sparrow E, et al.
J Med Chem
. 2021 Dec;
64(24):17795-17812.
PMID: 34908407
The 3,9-diazaspiro[5.5]undecane-based compounds and have previously been reported to be potent competitive γ-aminobutyric acid type A receptor (GABAR) antagonists showing low cellular membrane permeability. Given the emerging peripheral application of...
9.
Isensee J, van Cann M, Despang P, Araldi D, Moeller K, Petersen J, et al.
J Cell Biol
. 2021 Aug;
220(10).
PMID: 34431981
Depolarization drives neuronal plasticity. However, whether depolarization drives sensitization of peripheral nociceptive neurons remains elusive. By high-content screening (HCS) microscopy, we revealed that depolarization of cultured sensory neurons rapidly activates...
10.
Vasilopoulos G, Moser R, Petersen J, Aktas M, Narberhaus F
Biochim Biophys Acta Mol Cell Biol Lipids
. 2021 Mar;
1866(7):158926.
PMID: 33766680
Bacterial membranes are primarily composed of phosphatidylethanolamine (PE), phosphatidylglycerol (PG) and cardiolipin (CL). In the canonical PE biosynthesis pathway, phosphatidylserine (PS) is decarboxylated by the Psd enzyme. CL formation typically...