Jon J Vermeire
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Explore the profile of Jon J Vermeire including associated specialties, affiliations and a list of published articles.
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20
Citations
438
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Recent Articles
1.
Abriola L, Hoyer D, Caffrey C, Williams D, Yoshino T, Vermeire J
PLoS One
. 2019 Jun;
14(6):e0217019.
PMID: 31158236
Hookworms remain a major health burden in the developing world, with hundreds of millions currently afflicted by these blood-feeding parasites. There exists a vital need for the discovery of novel...
2.
Weeks J, Roberts W, Robinson K, Keaney M, Vermeire J, Urban Jr J, et al.
Int J Parasitol Drugs Drug Resist
. 2016 Oct;
6(3):314-328.
PMID: 27751868
The screening of candidate compounds and natural products for anthelmintic activity is important for discovering new drugs against human and animal parasites. We previously validated in Caenorhabditis elegans a microfluidic...
3.
Vermeire J, Suzuki B, Caffrey C
Pharmaceuticals (Basel)
. 2016 Jul;
9(3).
PMID: 27384569
Hookworm infection is chief among soil-transmitted helminthiases (STHs) for the chronic morbidly inflicted. Deworming via mass drug administration (MDA) programs most often employs single doses of benzimidazole drugs to which...
4.
Treger R, Otchere J, Keil M, Quagraine J, Rai G, Mott B, et al.
Am J Trop Med Hyg
. 2013 Dec;
90(1):71-4.
PMID: 24297811
A panel of 80 compounds was screened for anthelmintic activity against a laboratory strain of Ancylostoma ceylanicum and field isolates of hookworm obtained from school children in the Kintampo North...
5.
Rigouin C, Vermeire J, Nylin E, Williams D
Mol Biochem Parasitol
. 2013 Aug;
191(1):1-6.
PMID: 23916800
Hookworm disease is a debilitating worm infection that affects hundreds of millions of people. Despite the existence of anthelmintic drugs, reports have testified of a decrease in efficacy of these...
6.
Nguyen J, Pool C, Wong C, Treger R, Williams D, Cappello M, et al.
Chem Biol
. 2013 Jul;
20(8):991-1001.
PMID: 23891152
Hookworms are parasitic nematodes that have a devastating impact on global health, particularly in developing countries. We report a biochemical and structural analysis of a peroxiredoxin from the hookworm Ancylostoma...
7.
Davey D, Manickam N, Simms B, Harrison L, Vermeire J, Cappello M
Exp Parasitol
. 2012 Dec;
133(3):243-9.
PMID: 23232252
Hookworms are bloodfeeding intestinal nematodes that are a major cause of anemia in resource-limited countries. Despite repeated exposure beginning in early childhood, humans retain lifelong susceptibility to infection without evidence...
8.
Mott B, Cheng K, Guha R, Kommer V, Williams D, Vermeire J, et al.
Medchemcomm
. 2012 Dec;
3(12):1505-1511.
PMID: 23205265
Parasitic diseases continue to have a devastating impact on human populations worldwide. Lack of effective treatments, the high cost of existing ones, and frequent emergence of resistance to these agents...
9.
Vermeire J, Lantz L, Caffrey C
PLoS Negl Trop Dis
. 2012 Jul;
6(7):e1680.
PMID: 22802972
Background: Hookworm disease is a major global health problem and principal among a number of soil-transmitted helminthiases (STHs) for the chronic disability inflicted that impacts both personal and societal productivity....
10.
Cho Y, Vermeire J, Merkel J, Leng L, Du X, Bucala R, et al.
Chem Biol
. 2011 Sep;
18(9):1089-101.
PMID: 21944748
The screening of bioactive compound libraries can be an effective approach for repositioning FDA-approved drugs or discovering new pharmacophores. Hookworms are blood-feeding, intestinal nematode parasites that infect up to 600...