Conor R Caffrey
Overview
Explore the profile of Conor R Caffrey including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
163
Citations
3941
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Spaulding A, Sharma A, Giardini M, Hoffman B, Bernatchez J, McCall L, et al.
ACS Infect Dis
. 2025 Feb;
11(3):584-599.
PMID: 39936822
Neglected tropical diseases such as Chagas disease, human African trypanosomiasis, leishmaniasis, and schistosomiasis have a significant global health impact in predominantly developing countries, although these diseases are spreading due to...
2.
Nunes J, Santos-Junior P, Gomes M, Ferreira L, Padilha E, Teixeira T, et al.
Eur J Med Chem
. 2024 Dec;
283():117109.
PMID: 39653622
Trypanosoma cruzi (T. cruzi) and Trypanosoma brucei (T. brucei) urgently demand innovative drug development due to their impact on public health worldwide. Their cysteine proteases, Cruzain (CRZ) and the T....
3.
Liu L, Francisco K, Sun Y, Serafim M, Amarasinghe D, Teixeira T, et al.
ACS Infect Dis
. 2024 Nov;
10(12):4182-4193.
PMID: 39589805
The proteasome is essential for eukaryotic cell proteostasis, and inhibitors of the 20S proteasome are progressing preclinically and clinically as antiparasitics. We screened, the causative agent of human and animal...
4.
Fajtova P, Hurysz B, Miyamoto Y, Serafim M, Jiang Z, Vazquez J, et al.
Protein Sci
. 2024 Nov;
33(12):e5225.
PMID: 39589076
The protozoan parasite Trichomonas vaginalis (Tv) causes trichomoniasis, the most common non-viral sexually transmitted infection in the world. Although Tv has been linked to significant health complications, only two closely...
5.
Balogun E, Joseph G, Olabode S, Dayaso N, Danazumi A, Bashford-Rogers R, et al.
Pathogens
. 2024 Oct;
13(10).
PMID: 39452722
Human schistosomiasis, caused by the trematode, is a neglected parasitic disease affecting over 250 million people worldwide. There is no vaccine, and the single available drug is threatened by drug...
6.
Liu L, ODonoghue A, Caffrey C
Adv Parasitol
. 2024 Oct;
126:53-96.
PMID: 39448194
The proteasome is a proteolytically active molecular machine comprising many different protein subunits. It is essential for growth and survival in eukaryotic cells and has long been considered a drug...
7.
Liu L, Lucero B, Manriquez-Rodriguez C, Francisco K, Teixeira T, Yohannan D, et al.
ACS Omega
. 2024 Aug;
9(32):34829-34840.
PMID: 39157084
The 20S proteasome is a multimeric protease complex that is essential for proteostasis in the cell. Small molecule proteasome inhibitors are approved drugs for various cancers and are advancing clinically...
8.
Cogo R, Pavani T, Mengarda A, Cajas R, Teixeira T, Fukui-Silva L, et al.
ACS Omega
. 2024 Jun;
9(23):25356-25369.
PMID: 38882094
Schistosomiasis is a neglected disease of poverty that affects over 200 million people worldwide and relies on a single drug for therapy. The cathepsin B1 cysteine protease (SmCB1) of has...
9.
Ryu B, Glukhov E, Teixeira T, Caffrey C, Madiyan S, Joseph V, et al.
J Nat Prod
. 2024 Jun;
87(6):1601-1610.
PMID: 38832890
Kavaratamide A (), a new linear lipodepsipeptide possessing an unusual isopropyl--methylpyrrolinone moiety, was discovered from the tropical marine filamentous cyanobacterium collected from Kavaratti, India. A comparative chemogeographic analysis of ....
10.
Spiwokova P, Horn M, Fanfrlik J, Jilkova A, Fajtova P, Leontovyc A, et al.
ACS Infect Dis
. 2024 May;
10(6):1935-1948.
PMID: 38757505
Schistosomiasis, caused by a parasitic blood fluke of the genus is a global health problem for which new chemotherapeutic options are needed. We explored the scaffold of gallinamide A, a...