John W Weisel
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Explore the profile of John W Weisel including associated specialties, affiliations and a list of published articles.
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204
Citations
5751
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Recent Articles
11.
Chernysh I, Mukhopadhyay S, Johnson T, Brooks J, Sarkar R, Weisel J, et al.
J Thromb Haemost
. 2024 Mar;
22(6):1675-1688.
PMID: 38492853
Background: Deep vein thrombosis is a common vascular event that can result in debilitating morbidity and even death due to pulmonary embolism. Clinically, patients with faster resolution of a venous...
12.
Peshkova A, Weisel J, Litvinov R
J Thromb Haemost
. 2024 Feb;
22(6):1742-1748.
PMID: 38401713
Background: The platelet-driven contraction or retraction of blood clots has been utilized to obtain blood serum for laboratory studies, but now, in vitro clot contraction assays are used in research...
13.
Risman R, Belcher H, Ramanujam R, Weisel J, Hudson N, Tutwiler V
Biomolecules
. 2024 Feb;
14(2).
PMID: 38397467
Altered properties of fibrin clots have been associated with bleeding and thrombotic disorders, including hemophilia or trauma and heart attack or stroke. Clotting factors, such as thrombin and tissue factor,...
14.
Griffin M, Dahlgren A, Nagaswami C, Litvinov R, Keeler K, Madenjian C, et al.
J Thromb Haemost
. 2023 Dec;
22(4):1056-1068.
PMID: 38160724
Background: Blood clots are primarily composed of red blood cells (RBCs), platelets/thrombocytes, and fibrin. Despite the similarities observed between mammals and zebrafish, the composition of fish thrombi is not as...
15.
Schepers L, Chernysh I, Albrecht C, Browning L, Hillsdon-Smith M, Cox A, et al.
JVS Vasc Sci
. 2023 Dec;
4:100105.
PMID: 38077164
Aortic dissection occurs when a weakened portion of the intima tears, and a separation of layers propagates along the aortic wall to form a false lumen filled with active blood...
16.
Megakaryocyte-induced contraction of plasma clots: cellular mechanisms and structural mechanobiology
Kim O, Litvinov R, Gagne A, French D, Brass L, Weisel J
Blood
. 2023 Nov;
143(6):548-560.
PMID: 37944157
Nonmuscle cell contractility is an essential feature underlying diverse cellular processes such as motility, morphogenesis, division and genome replication, intracellular transport, and secretion. Blood clot contraction is a well-studied process...
17.
Michael C, Pancaldi F, Britton S, Kim O, Peshkova A, Vo K, et al.
Commun Biol
. 2023 Aug;
6(1):869.
PMID: 37620422
While blood clot formation has been relatively well studied, little is known about the mechanisms underlying the subsequent structural and mechanical clot remodeling called contraction or retraction. Impairment of the...
18.
19.
Ramanujam R, Maksudov F, Litvinov R, Nagaswami C, Weisel J, Tutwiler V, et al.
Adv Healthc Mater
. 2023 Aug;
12(27):e2300096.
PMID: 37611209
Fibrin provides the main structural integrity and mechanical strength to blood clots. Failure of fibrin clots can result in life-threating complications, such as stroke or pulmonary embolism. The dependence of...
20.
Evtugina N, Peshkova A, Khabirova A, Andrianova I, Abdullayeva S, Ayombil F, et al.
J Thromb Haemost
. 2023 Jun;
21(9):2418-2429.
PMID: 37268065
Background: Piezo1 is a mechanosensitive cationic channel that boosts intracellular [Ca]. Compression of red blood cells (RBCs) during platelet-driven contraction of blood clots may cause the activation of Piezo1. Objectives:...